Incidence of acute ischemic cerebrovascular events in a cohort of HIV-infected patients.

Acta neurologica Belgica
Anda EilamRonit Gilad

Abstract

The prevalence of vascular diseases in HIV (human immunodeficiency virus)-infected individuals has been comprehensively investigated. However, their incidence of ischemic cerebrovascular events has not been thoroughly examined. Our aim was to examine the rate of ischemic stroke or TIA (transient ischemic attack) in a defined HIV population and to find the risk factors that are characteristic in this population. A case-controlled retrospective cohort study of HIV patients followed up at Kaplan Medical Center between 2009 and 2017 was performed. The study included 300 patients who had been compared to a matched age and gender group. The data were collected by reviewing patients' files and imaging studies. The first goal was to compare the incidence of ischemic cerebrovascular events in both groups. Secondary endpoints were to characterize the types of cerebrovascular events and risk factors in the study group versus the general population. There were more ischemic stroke cases in the study group vs. the control group. After adjusting for vascular risk factors in a multivariate analysis, the odds ratio for a cerebrovascular accident in the HIV patient group was 2.29 (p = 0.057). Notably, in the comparative group, the vascular risk...Continue Reading

References

Mar 1, 1991·Stroke; a Journal of Cerebral Circulation·P A WolfW B Kannel
Mar 1, 1996·Stroke; a Journal of Cerebral Circulation·A N Pinto
Apr 3, 1999·Stroke; a Journal of Cerebral Circulation·R BrillaI W Husstedt
Sep 8, 2000·Stroke; a Journal of Cerebral Circulation·M D ConnorR D Brettle
Jul 12, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marianne SavèsUNKNOWN French WHO MONICA Project and the APROCO (ANRS EP11) Study Group
Dec 20, 2003·Stroke; a Journal of Cerebral Circulation·John W ColeSteven J Kittner
Apr 26, 2007·The Journal of Clinical Endocrinology and Metabolism·Virginia A TriantSteven K Grinspoon
Jun 15, 2010·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Nina Friis-MøllerUNKNOWN DAD study group
May 15, 2012·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Felicia C ChowVirginia A Triant
Sep 22, 2012·Lancet Neurology·Laura A BenjaminMyles D Connor
Jan 19, 2013·American Journal of Public Health·Sean Cahill, Robert Valadéz
Apr 5, 2013·Therapeutic Advances in Chronic Disease·Elyse J SingerMargrit Carlson
May 9, 2013·Stroke; a Journal of Cerebral Circulation·Ralph L SaccoUNKNOWN Council on Nutrition, Physical Activity and Metabolism
Jun 3, 2014·The Lancet Infectious Diseases·Jennifer E FugateFarrah J Mateen
Apr 12, 2015·Neurology·Jason J SicoUNKNOWN Veterans Aging Cohort Study
Jun 14, 2015·The Lancet Infectious Diseases·Mikaela SmitUNKNOWN ATHENA observational cohort
Sep 1, 2015·The Canadian Journal of Cardiology·Karen YeatesOlugbenga Ogedegbe
Aug 19, 2016·HIV Medicine·A Silva-PintoP Abreu

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.