Abstract
Anemia is a hematologic abnormality commonly discussed during the treatment of childhood cancer, but its incidence has not been previously reported. As the basis for determining the incidence of anemia, this retrospective review of medical records combined databases containing the records of all patients 1 to 18 years of age with newly diagnosed neuroblastoma, rhabdomyosarcoma, Hodgkin disease, Ewing sarcoma, or osteosarcoma from two pediatric oncology centers. Data from 405 patients were included in the analysis of hemoglobin at the time of diagnosis. Across diagnoses, 51% to 74% of patients were anemic using the Centers for Disease Control and Prevention age- and sex-specific values to define anemia. The long-term complications of anemia in children with cancer are unknown. Further investigation of the clinical significance of anemia, including its impact on quality of life, is warranted.
References
May 1, 1992·The Medical Clinics of North America·D A Sears
Nov 1, 1991·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·L C PlataniasM J Ratain
Jun 14, 1990·The New England Journal of Medicine·C B MillerJ L Spivak
Sep 1, 1989·CA: a Cancer Journal for Clinicians·D Steinberg
Jul 1, 1994·The American Journal of the Medical Sciences·W R ReedR L DeGowin
May 1, 1994·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·S CascinuG Catalano
Feb 1, 1996·Transfusion·C WurnigR W Kurz
Apr 1, 1996·Hematology/oncology Clinics of North America·A R Moliterno, J L Spivak
Aug 26, 1996·The American Journal of Medicine·A G Greenburg
Nov 1, 1996·Transfusion·T M MaraniS G Sandler
Mar 26, 1997·JAMA : the Journal of the American Medical Association·A C LookerC L Johnson
Aug 12, 1998·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·M Hockenberry-EatonJ Taylor
Oct 2, 1998·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Y FangC Zhou
May 20, 1999·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·H Ludwig
Oct 8, 1999·Journal of the National Cancer Institute·J E Groopman, L M Itri
Citations
Feb 5, 2014·Anesthesiology Clinics·Gregory J Latham
Mar 5, 2010·Paediatric Anaesthesia·Gregory J Latham, Robert S Greenberg
Mar 23, 2015·Blood Reviews·Neil ShahLawrence Tim Goodnough
Apr 28, 2004·Clinical Journal of Oncology Nursing·Jeanne M Erickson
Jul 25, 2007·Cancer·Hervé SarteletGilles Vassal
Feb 20, 2019·Pediatric Hematology and Oncology·Irini D BatsisDaniel A Weiser