Incidence of anemia in children with solid tumors or Hodgkin disease

Journal of Pediatric Hematology/oncology
Marilyn J HockenberryBassem Razzouk

Abstract

Anemia is a hematologic abnormality commonly discussed during the treatment of childhood cancer, but its incidence has not been previously reported. As the basis for determining the incidence of anemia, this retrospective review of medical records combined databases containing the records of all patients 1 to 18 years of age with newly diagnosed neuroblastoma, rhabdomyosarcoma, Hodgkin disease, Ewing sarcoma, or osteosarcoma from two pediatric oncology centers. Data from 405 patients were included in the analysis of hemoglobin at the time of diagnosis. Across diagnoses, 51% to 74% of patients were anemic using the Centers for Disease Control and Prevention age- and sex-specific values to define anemia. The long-term complications of anemia in children with cancer are unknown. Further investigation of the clinical significance of anemia, including its impact on quality of life, is warranted.

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Citations

Feb 5, 2014·Anesthesiology Clinics·Gregory J Latham
Mar 5, 2010·Paediatric Anaesthesia·Gregory J Latham, Robert S Greenberg
Mar 23, 2015·Blood Reviews·Neil ShahLawrence Tim Goodnough
Apr 28, 2004·Clinical Journal of Oncology Nursing·Jeanne M Erickson
Jul 25, 2007·Cancer·Hervé SarteletGilles Vassal

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Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

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