Incidence of auto-immune pemphigus in the Midi-Pyrénées region in 2002-2006

Dermatology : International Journal for Clinical and Investigative Dermatology
M ThomasN Meyer

Abstract

Auto-immune pemphigus is an organ-specific immune disorder due to pathogenic auto-antibodies. Both genetic and environmental factors have been associated with the occurrence of auto-immune pemphigus. Little is known about the epidemiology of auto-immune pemphigus in western Europe. To evaluate the incidence of auto-immune pemphigus in south-western France (namely the Midi-Pyrénées region) in a 5-year period between 2002 and 2006. We performed a retrospective study of the annual incidence of auto-immune pemphigus diagnosed in the Midi-Pyrénées region, between January 1, 2002, and December 31, 2006. Possible cases of pemphigus were initially selected using skin direct immunofluorescence (DIF) databases from all laboratories in the Midi-Pyrénées region. Systematic validation of all cases was performed by two of the authors (N.M., M.T.). To qualify as a case of auto-immune pemphigus, patients had to fulfil the following criteria: history of clinical signs of pemphigus as assessed by a dermatologist and a positive DIF. To be included in the study, validated cases of auto-immune pemphigus had to fulfil the following criteria: the date of first positive skin DIF between January 1, 2002, and December 31, 2006, and patient living in the...Continue Reading

Citations

Feb 9, 2012·Cutaneous and Ocular Toxicology·Kübra Bozdag, İlgül Bilgin
Sep 20, 2011·Dermatologic Clinics·Nicolas MeyerPascal Joly
Nov 10, 2009·Autoimmunity Reviews·N Meyer, L Misery
Mar 21, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·S BalicaC Paul
May 17, 2013·International Journal of Dermatology·Nadège CordelBenoît Tressières

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