PMID: 9524703Apr 3, 1998Paper

Incidence of axillary lymph node metastases in T1a and T1b breast carcinoma

Annals of Surgical Oncology
E R PortK J Van Zee

Abstract

We investigated the incidence of axillary lymph node metastases in patients with T1a (< or = 0.5 cm) and T1b (> 0.5 cm and < or = 1.0 cm) breast cancers. The charts of 2000 patients who underwent axillary lymph node dissection for breast cancer at our institution from 1989 to 1991 were reviewed. Of these, 81 patients had T1a and 166 had T1b primary breast cancers. Among the 247 patients with T1a and T1b breast cancers, nodal metastases were present in 30 (12.1%), with a 7.4% positivity rate for patients with T1a and 14.5% positivity rate for T1b tumors. Of the 212 patients who had > or = 10 nodes dissected, 29 (13.7%) had positive nodes. Of those, 6 of 60 (10.0%) patients with T1a and 23 of 152 (15.1%) with T1b tumors had positive nodes. The presence of lymphovascular invasion (LVI) predicted a significantly higher nodal positivity rate (27.8% vs. 10.9%, p = 0.05). Of patients with adequately evaluated axillae, 10% with T1a and 15% with T1b cancers were found to have nodal metastases. Although LVI was significantly associated with a higher risk of lymph node metastases, we could not characterize any subgroup at acceptably low risk of nodal positivity. Until a more useful prognostic indicator is discovered, axillary dissection s...Continue Reading

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Citations

Jan 1, 2010·Indian Journal of Surgical Oncology·Rajshekhar C JakaR V Parameswaran
Dec 5, 1998·Japanese Journal of Clinical Oncology·Y IwasakiH Tsuda
Sep 24, 1999·Annals of Surgical Oncology·G B MannK J Van Zee
Nov 25, 2000·Breast Cancer : the Journal of the Japanese Breast Cancer Society·S MitsuyamaY Hachitanda
Aug 6, 2003·Annals of Surgical Oncology·Tzu-Chieh ChaoShin-Cheh Chen
Aug 14, 2012·Current Problems in Cancer·Kathryn T Chen
Sep 10, 2002·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·J BevilacquaK J Van Zee
Aug 1, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·José Luiz B BevilacquaKimberly J Van Zee
Nov 24, 2004·Journal of the American College of Surgeons·Julie KeppleV Suzanne Klimberg
Mar 11, 2004·The Breast Journal·Richard L EllisGary L Dunnington
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Dec 1, 2020·Current Problems in Diagnostic Radiology·Kyungmin Shin, Gary J Whitman

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