PMID: 8994402Dec 1, 1996Paper

Incidence of childhood leukaemia and non-Hodgkin's lymphoma in the vicinity of nuclear sites in Scotland, 1968-93

Occupational and Environmental Medicine
L SharpP A McKinney

Abstract

The primary aims were to investigate the incidence of leukaemia and non-Hodgkin's lymphoma in children resident near seven nuclear sites in Scotland and to determine whether there was any evidence of a gradient in risk with distance of residence from a nuclear site. A secondary aim was to assess the power of statistical tests for increased risk of disease near a point source when applied in the context of census data for Scotland. The study data set comprised 1287 cases of leukaemia and non-Hodgkin's lymphoma diagnosed in children aged under 15 years in the period 1968-93, validated for accuracy and completeness. A study zone around each nuclear site was constructed from enumeration districts within 25 km. Expected numbers were calculated, adjusting for sex, age, and indices of deprivation and urban-rural residence. Six statistical tests were evaluated. Stone's maximum likelihood ratio (unconditional application) was applied as the main test for general increased incidence across a study zone. The linear risk score based on enumeration districts (conditional application) was used as a secondary test for declining risk with distance from each site. More cases were observed (O) than expected (E) in the study zones around Rosyth n...Continue Reading

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Citations

Jun 24, 2003·Occupational and Environmental Medicine·A Silva-MatoM Viana
Oct 27, 2011·American Journal of Public Health·Jean D BrenderJayajit Chakraborty
Jan 1, 2011·Archives of Environmental & Occupational Health·Fangchao MaTiefu Shen
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Jan 10, 2012·International Journal of Cancer. Journal International Du Cancer·Claire Sermage-FaureJacqueline Clavel
Jan 17, 2014·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Adelheid SoubrySusan K Murphy
Nov 18, 2005·Blood·Kevin G Leong, Aly Karsan
Dec 31, 2016·Radiation and Environmental Biophysics·Xi GongYan Lin

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