Incidence of childhood-onset type 1 diabetes in Biscay, Spain, 1990-2013

Pediatric Diabetes
Concepción Fernández-RamosItxaso Rica

Abstract

To identify the incidence rate (IR) and epidemiologic trends of childhood type 1 diabetes mellitus (T1DM) in children aged 0 to 14-yr-old from 1990 to 2013, in the north of Spain (Biscay). A prospective-retrospective study was performed. Capture-recapture method was used: primary cases were ascertained from hospital register and a secondary independent data source was obtained from diabetes associations and public health plan database. Age and sex-standardized incidence rates were calculated using direct method, assuming an equal distribution in each age/sex group. In order to identify and analyse trends the period studied was divided into two (1990-2001 and 2002-2013) 11-year periods. The 95% confidence interval (CI) was estimated assuming the Poisson distribution. A total of 399 new cases were identified throughout the study. Mean age at diagnosis was 8.9 ± 3.7 yr. Completeness of ascertainment was 99.1%. Mean annual age-standardized IR was 10.7 (95% CI: 9.6-11.7). The mean incidence for the 0-4, 5-9 and 10-14 age groups was 5.1, 14.6 and 13.2 per 100,000 children/yr, respectively. The incidence rate trend in the whole group was not statistically significant. In the 10-14 age group we found a yearly average increase (2.5% [CI...Continue Reading

References

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Aug 7, 2013·JAMA : the Journal of the American Medical Association·Valma HarjutsaloPer-Henrik Groop

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Citations

Apr 20, 2016·Journal of Diabetes Research·F FortunatoUNKNOWN Apulian Childhood-Onset Diabetes Registry Workgroup
Dec 17, 2016·Pediatric Diabetes·Azza A ShaltoutUNKNOWN Steering Group for the Study of Childhood Diabetes in Kuwait
Mar 4, 2017·Diabetic Medicine : a Journal of the British Diabetic Association·A ChobotP Jarosz-Chobot
Sep 13, 2018·Diabetes/metabolism Research and Reviews·Ying XiaZhiguang Zhou
Jan 18, 2020·Pediatric Diabetes·Ihsan Esen, Deniz Okdemir
Oct 11, 2017·Scientific Reports·Yin-Ling ChenHai-Lu Zhao

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