The incidence of congenital heart disease (CHD) in the Western industrialized world has varied from a low value of about 3 to 5 per 1000 live births to about 12 per 1000 live births. Most of the lower incidence figures were obtained before there were sufficiently well trained pediatric cardiologists and before the success of cardiac surgery put a premium on early and correct diagnosis of CHD. The advent of echocardiography with Doppler color flow measurements has made it possible to diagnose lesions that are asymptomatic, minor, and even without murmurs. Given these differences, there does not appear to have been a significant increase in the incidence of CHD over the last 20-30 years. The incidence of CHD in underdeveloped countries is not known, but the distribution of different lesions is fairly similar to those in developed countries except perhaps for fewer with aortic stenosis and coarctation of the aorta.
Death certificate reports of cardiovascular disorders in children: comparison with diagnoses in a pediatric cardiology registry
Incidence and natural course of trabecular ventricular septal defect: two-dimensional echocardiography and color Doppler flow imaging study
White-black differences in cardiovascular malformations in infancy and socioeconomic factors. The Baltimore-Washington Infant Study Group
Molluscicidal trials and correlation between the presence of Tetrapleura tetraptera in an area and the absence of the intermediate hosts of schistosomiasis and fascioliasis in southwest Nigeria
Prevalence, treatment, and outcome of heart disease in live-born children: a prospective analysis of 91,823 live-born children
Evaluation of a temporal increase in ventricular septal defects: estimated prevalence and severity in northeastern New York, 1970-1983
Congenital heart disease: incidence in the first year of life. The Alberta Heritage Pediatric Cardiology Program
Frequency of various congenital heart diseases in Chinese adults: analysis of 926 consecutive patients over 13 years of age
Natural history of congenital heart disease. Problems in its assessment with special reference to ventricular septal defects
Maternal age specific rates for chromosome aberrations and factors influencing them: report of a collaborative european study on 52 965 amniocenteses
Intracellular potential and K+ activity in rat kidney proximal tubular cells in acidosis and K+ depletion
Congenital heart disease among 160 480 liveborn children in Liverpool 1960 to 1969. Implications for surgical treatment
Optical coherence tomography-current technology and applications in clinical and biomedical research
Atrial standstill causing congestive heart failure in a child with ostium secundum atrial septal defect.
Studies on morphogenesis and visualization of the early embryonic heart with regard to the development of conotruncal heart defects
Association of a tandem repeat polymorphism in NFATc1 with increased risk of perimembranous ventricular septal defect in a Chinese population
Assessment of pulmonary valve and right ventricular outflow tract with real-time three-dimensional echocardiography
Pulmonary artery remodeling in transposition of the great arteries: relevance for neoaortic root dilatation
Current and potential impact of fetal diagnosis on prevalence and spectrum of serious congenital heart disease at term in the UK. British Paediatric Cardiac Association
Increased nuchal translucency and congenital heart defects in euploid fetuses. The Szeged experience
The Edgar Mannheimer Memorial lecture. From Maude to Claude: the musings of an insomniac in the era of evidence-based medicine
Is the function of all cardiac valves after the arterial switch operation influenced by an associated ventricular septal defect?
Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3
NFATc1 mediates vascular endothelial growth factor-induced proliferation of human pulmonary valve endothelial cells.
Prophylaxis with palivizumab against respiratory syncytial virus infection in infants with congenital heart disease--who should receive it?
Identification of two novel mutations of the HOMEZ gene in Chinese patients with isolated ventricular septal defect
Transforming growth factor β, bone morphogenetic protein, and vascular endothelial growth factor mediate phenotype maturation and tissue remodeling by embryonic valve progenitor cells: relevance for heart valve tissue engineering.
Clinical characterization of 42 oligospermic or azoospermic men with microdeletion of the AZFc region of the Y chromosome, and of 18 children conceived via ICSI
Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.
Aortic coarctation is a congenital condition characterized by narrowing of the aorta. Discover the latest research on this disease here.