Incidence of diarrhea and associated risk factors in patients with traumatic brain injury and enteral nutrition

Metabolic Brain Disease
Luiza Valois VieiraRaquel Rocha

Abstract

To determine the occurrence of diarrhea and associated factors in critically ill patients with traumatic brain injury (TBI) in use of nutritional therapy. Prospective cohort study conducted in an Intensive Care Unit (ICU) of a General Hospital reference in trauma. We evaluated TBI patients who stayed less than 72 h in the ICU, who were using EN for at least 48 h. Definition of diarrhea it was considered three or more episodes of liquid stools or semi-liquid at 24 h. For analysis were evaluated demographic, epidemiological, clinical and nutritional data. Twenty-three patients were evaluated, being 86.9% male, median 33 years old (IQR = 25-52 years) and 16-day ICU stay (IQR = 10-26 days). Diarrhea occurred in 69.6% of the patients and they had a longer time in the ICU (p = 0.007). All patients who used combination prokinetic therapy (metoclopramide and erythromycin) and used antibiotics for more than 8 days had diarrhea (p = 0.057 and p = 0.007, respectively). The incidence of diarrhea was high in TBI patients with enteral nutrition and was associated with the use of antibiotics for more than one week.

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Citations

Jan 22, 2021·Critical Care : the Official Journal of the Critical Care Forum·Laurent CarteronGuillaume Besch
Mar 9, 2021·Journal of Gastroenterology and Hepatology·Pimsiri SripongpunChanon Kongkamol
May 6, 2021·BMC Pediatrics·Ying ZhouWeibing Tang
Jun 16, 2021·The Journal of Clinical Investigation·Marie HanscomTerez Shea-Donohue

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Methods Mentioned

BETA
SMA

Software Mentioned

Statistical Package for the Social Science ( SPSS )

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