PMID: 16633231Apr 25, 2006Paper

Incidence of disc hemorrhages in open-angle glaucoma before and after trabeculectomy

Journal of Glaucoma
Tomoko MiyakeYoshiaki Kitazawa

Abstract

To investigate the effects of reduction of intraocular pressure (IOP) by surgical intervention on the frequency of disc hemorrhages in eyes with primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG). Retrospective study. We studied 99 eyes of 99 patients with POAG and 50 eyes of 50 patients with NTG, who underwent trabeculectomy with adjunctive mitomycin C (MMC) and were followed regularly at 1 to 3-month intervals at the Glaucoma Service of Gifu University Hospital. We applied Kaplan-Meier life-table analysis for the detection of disc hemorrhages before and after trabeculectomy. Trabeculectomy significantly reduced IOP (in POAG: 19.6 +/- 4.4 down to 11.1 +/- 4.2 mm Hg; in NTG: 15.3 +/- 1.5 down to 11.3 +/- 4.5 mm Hg; mean +/- SD). Life-table analysis revealed that the final cumulative probability of detecting a disc hemorrhage after surgery in POAG was 5.5 +/- 2.2% (calculated probability +/- SE) and was significantly lower than that (33.4 +/- 7.8%) before surgery (P < 0.0001, log-rank test). Likewise, the final probability after surgery in NTG was 23.1 +/- 6.3% and was significantly lower than that (42.1 +/- 8.8%) before surgery (P = 0.0063, log-rank test). IOP reduction via surgical intervention significantly ...Continue Reading

References

Apr 1, 1979·American Journal of Ophthalmology·H A Quigley, A E Maumenee
Feb 1, 1977·Archives of Ophthalmology·S M DranceM S Kottler
Jun 1, 1976·American Journal of Ophthalmology·L C Chumbley, R F Brubaker
Jun 1, 1991·The Tohoku Journal of Experimental Medicine·Y KoiwaT Takishima
Dec 1, 1991·Archives of Ophthalmology·Y KitazawaM Minobe
Mar 1, 1989·Survey of Ophthalmology·S M Drance
Jun 1, 1986·Ophthalmology·Y KitazawaT Yamamoto
Jun 1, 1973·Archives of Ophthalmology·S M DranceF Feldman
Feb 1, 1971·The British Journal of Ophthalmology·I S BeggV P Sweeney
Apr 1, 1981·Archives of Ophthalmology·H A QuigleyA E Maumenee
Sep 1, 1983·Archives of Ophthalmology·J Flammer, S M Drance
Mar 1, 1982·Ophthalmology·Z M ShihabP Hay
Sep 1, 1982·Ophthalmology·W M Grant, J F Burke
Feb 1, 1981·Acta Ophthalmologica·B BengtssonC E Krakau
Jul 1, 1981·The British Journal of Ophthalmology·J Gloster
Jan 1, 1980·Acta Ophthalmologica·B Bengtsson
May 1, 1980·Survey of Ophthalmology·R Z Levene
Jul 15, 1994·American Journal of Ophthalmology·J B Jonas, L Xu
Jul 1, 1996·Ophthalmology·S W Siegner, P A Netland
Sep 28, 1998·Japanese Journal of Ophthalmology·L DaugelieneY Kitazawa
Jan 1, 1999·Journal of Glaucoma·K IshidaY Kitazawa
Aug 6, 2000·American Journal of Ophthalmology·K IshidaY Kitazawa
Jun 1, 2001·American Journal of Ophthalmology·S DranceUNKNOWN Collaborative Normal-Tension Glaucoma Study Group
Jul 1, 1994·Journal of Glaucoma·K SugiyamaE M Van Buskirk

❮ Previous
Next ❯

Citations

Feb 11, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Akira Sawada, Tetsuya Yamamoto
Nov 28, 2012·Japanese Journal of Ophthalmology·Ho Soong KimJoohyun Park
Oct 26, 2013·Survey of Ophthalmology·Min Hee Suh, Ki Ho Park
Aug 12, 2008·Ophthalmology·Boel BengtssonUNKNOWN EMGT Group
Aug 19, 2007·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Joseph San Laureano
Aug 9, 2011·Clinical & Experimental Ophthalmology·Paul Healey
Feb 4, 2011·Acta Ophthalmologica·Zeba A SyedRobert Ritch
Apr 13, 2015·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Hussain Y PatelGraham E Trope
Nov 12, 2016·American Journal of Ophthalmology·Donald L BudenzUNKNOWN Ocular Hypertension Treatment Study Group
Apr 19, 2017·The British Journal of Ophthalmology·Akira SawadaChisato Nagata
Oct 5, 2018·Acta Ophthalmologica·Ewa Kosior-JareckaTomasz Żarnowski
Feb 28, 2008·Current Opinion in Ophthalmology·Tara A Uhler, Jody Piltz-Seymour
Mar 1, 2012·Asia-Pacific Journal of Ophthalmology·Carlos Gustavo De MoraesRobert Ritch
Jun 14, 2020·Acta Ophthalmologica·Rei SakataUNKNOWN for Lower Normal Pressure Glaucoma Study Members in Japan Glaucoma Society

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.