Incidence of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in patients with urinary tract infection

São Paulo Medical Journal = Revista Paulista De Medicina
Sobhan GhafourianNourkhoda Sadeghifard

Abstract

Resistant bacteria are emerging worldwide as a threat to favorable outcomes from treating common infections in community and hospital settings. The present investigation was carried out to study the incidence of extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae in patients with urinary tract infection in different seasons of the year, in order to determine the prevalence of the genes blaTEM, blaSHV and blaCTX-M, which are responsible for ESBL production among ESBL-producing K. pneumoniae, in three cities in Iran, and to investigate the antimicrobial susceptibility pattern of K. pneumoniae in different seasons. Retrospective study carried out among patients with urinary tract infections in five hospitals in Iran. Two hundred and eighty-eight clinical isolates of K. pneumoniae were collected between March 2007 and April 2008 from five hospitals in three cities in Iran. ESBLs were identified by phenotypic and genotypic methods. ESBL-producing Klebsiella pneumoniae were evaluated against non-beta-lactam antibiotics. Genes coding for ESBLs (blaSHV, TEM and CTX-M) were screened. Among the 288 clinical isolates of K. pneumoniae, 37.7%, 46.7% and 15.6% were obtained from hospitals in Ilam, Tehran and Tabriz, respe...Continue Reading

References

Jul 1, 1995·The Journal of Antimicrobial Chemotherapy·D Sirot
Oct 1, 1995·Clinical Microbiology Reviews·D M Livermore
Mar 18, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D L PatersonV L Yu
Oct 15, 2005·Clinical Microbiology Reviews·David L Paterson, Robert A Bonomo

❮ Previous
Next ❯

Citations

Oct 16, 2015·São Paulo Medical Journal = Revista Paulista De Medicina·José Carlos Carraro-EduardoCarlos Augusto Faria

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.