Incidence of HIV and the prevalence of HIV, hepatitis B and syphilis among youths in Maputo, Mozambique: a cohort study

PloS One
Edna ViegasNafissa Osman

Abstract

Prevalence of HIV in Mozambique among individuals aged 15-49 years is 11.5%. The HIV prevalence is higher in women than in men across the country, peaking at ages 25-29 years and 35-39 years, respectively. In this study, we aimed at determining the prevalence and incidence of HIV, prevalence of Hepatitis B (HBV), and prevalence of syphilis in youths. We also characterized a cohort of youths for future participation in phase I/II HIV vaccine trials. The study was conducted at a youth clinic in Maputo Central Hospital from August 2009 to October 2011. Youths of both genders aged 18-24 years (n = 1380) were screened for HIV using a sequential algorithm of two immunochromatographic assays, HBV using an enzyme linked immunosorbant test, and syphilis using a treponemal immunochromatographic strip test. The HIV seronegative participants (n = 1309) were followed-up for 12 months with quarterly study visits. The clinical and behavioral data were collected using structured questionnaires. The HIV seroconversions were confirmed by a molecular assay. The study population was female dominant (76.8%). All participants had a formal education, with 44.6% studying for technical or higher education degrees. The mean age at sexual debut was 16.6 ...Continue Reading

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Citations

Mar 21, 2016·Revista clínica española·J A Cuenca-GómezM T Cabezas-Fernández
Oct 1, 2020·Memórias do Instituto Oswaldo Cruz·Nédio MabundaIlesh Jani
Feb 7, 2020·International Journal of Environmental Research and Public Health·Rachid MuleiaChristel Faes
Nov 3, 2016·Tropical Medicine & International Health : TM & IH·Carolyn M AudetFelisbela Gaspar

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Methods Mentioned

BETA
enzyme linked immunosorbent assay

Software Mentioned

MySQL
INSIDA
Stata

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