Incidence of hypospadia and epispadia in chromatin-positive men.

Andrologia
J Raboch

Abstract

There are described some results of examination of three patients with a Klinefelter's syndrome two of whom had a heavy form of hypospadia, and one suffered from epispadia. The disturbances of penis development are explained, with respect to findings in adult age, by the insensibility of target tissues to the effect of testicular androgen. This insensibility was already acting in the third month of intrauterine life of the fetus.

References

Jul 15, 1968·American Journal of Obstetrics and Gynecology·J E JirásekJ Uher

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Citations

Jul 21, 2007·Hormone Research·Yung Seng LeeIeuan A Hughes
Jan 1, 1976·Andrologia·J RabochL Starka
Jan 24, 2009·Birth Defects Research. Part A, Clinical and Molecular Teratology·Michael LudwigSimeon A Boyadjiev
Sep 1, 1982·European Journal of Pediatrics·E TopperZ Laron
Aug 28, 2021·Genes·Glenda M BeamanWilliam G Newman

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