PMID: 6407427Feb 1, 1983Paper

Incidence of induced coronary artery spasm in recent acute transmural myocardial infarction

Archives des maladies du coeur et des vaisseaux
J M LablancheM E Bertrand

Abstract

A number of studies have suggested that coronary spasm may play a role in the genesis of myocardial infarction. We carried out a provocation test with 0,4 mg intravenous methylergometrine in 131 patients undergoing routine coronary angiography at least 6 weeks after transmural myocardial infarction. The 124 men and 7 women of equal mean age of 49,6 years underwent the investigation on average 27 +/- 9 days after the date of onset of myocardial infarction. Seventy four patients had anterior infarcts (antero septal, anterior, apical), 55 had inferior infarcts (inferior, diaphragmatic and true posterior) and 2 had lateral wall infarcts. Thirty two patients with anterior infarcts (45 p. cent) had a single vessel disease of the left anterior descending artery, 19 had double vessel disease (25 p. cent), 16 had triple vessel disease (21,6 p. cent). During the provocation test with methylergometrine, 13 patients (17,6 p. cent) developed a spasm, 6 on the left anterior descending, 6 on the right coronary and 1 on the left circumflex artery. The patients with insignificant coronary lesions (7 cases) did not develop focal spasm. Twenty seven patients with inferior infarcts (49 p. cent) had single vessel disease, 19 had double vessel disea...Continue Reading

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