Incidence of major hemorrhage after aggressive image-guided liver mass biopsy in the era of individualized medicine

Abdominal Radiology
James H BoyumA Nicholas Kurup

Abstract

To analyze a large volume of image-guided liver mass biopsies to assess for an increased incidence of major hemorrhage after aggressive liver mass sampling, and to determine if coaxial technique reduces major hemorrhage rate. Patients who underwent image-guided liver mass biopsy over a 15-year period (December 7, 2001-September 22, 2016) were retrospectively identified. An aggressive biopsy was defined as a biopsy event in which ≥ 4 core needle passes were performed. Association of major hemorrhage after aggressive liver mass biopsy and other potential risk factors of interest were assessed using logistic regression analysis. For the subset of aggressive biopsies, Fisher's exact test was used to compare the incidence of major hemorrhage using coaxial versus noncoaxial techniques. Aggressive biopsies constituted 11.6% of biopsy events (N =579/5011). The incidence of major hemorrhage with <4 passes was 0.4% (N =18/4432) and with ≥4 passes 1.2% (N =6/579). In univariable models, aggressive biopsy was significantly associated with major hemorrhage (OR 3.0, 95% CI 1.16-6.92, p =0.025). After adjusting for gender and platelet count, the association was not significant at the p =0.05 level (OR 2.58, 95% CI 0.927-6.24, p =0.067). The r...Continue Reading

References

Dec 1, 1990·American Journal of Clinical Pathology·P A McVay, P T Toy
Sep 1, 2005·Transfusion·Jodi B SegalUNKNOWN Transfusion Medicine/Hemostasis Clinical Trials Network
Feb 27, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Don C RockeyUNKNOWN American Association for the Study of Liver Diseases
Nov 26, 2009·AJR. American Journal of Roentgenology·Stacy D O'ConnorThomas C Winter
Feb 23, 2010·AJR. American Journal of Roentgenology·Thomas D AtwellTimothy J Welch
Jun 29, 2013·Journal of Vascular and Interventional Radiology : JVIR·Dustyn MarshallRobert K Kerlan
Jul 16, 2014·Seminars in Oncology·Barbara A Conley, James H Doroshow
Nov 21, 2015·The Cancer Journal·Bibiana I FerreiraWolfgang Link
Feb 4, 2016·Mayo Clinic Proceedings·James H BoyumPatrick S Kamath
Feb 26, 2016·Abdominal Radiology·Marc KohliKumar Sandrasegaran
Mar 28, 2016·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Vania TacherThierry De Baère
Nov 22, 2016·The Cancer Journal·Etay ZivStephen B Solomon
Sep 21, 2017·Abdominal Radiology·Douglas R KitchinJ Louis Hinshaw

❮ Previous
Next ❯

Citations

Nov 13, 2019·AJR. American Journal of Roentgenology·Matthew ElissaPerry J Pickhardt
Mar 24, 2021·Radiology·Aileen O'Shea, Theodore T Pierce
Oct 5, 2020·Journal of Vascular and Interventional Radiology : JVIR·Rahul A ShethSanjay Gupta
Jul 30, 2021·Abdominal Radiology·Edward M LawrenceMichael P Hartung

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.