Incidence of Seromas and Infections Using Fenestrated versus Nonfenestrated Acellular Dermal Matrix in Breast Reconstructions

Plastic and Reconstructive Surgery. Global Open
David A PalaiaMichael H Rosenberg

Abstract

Acellular dermal matrices (ADMs) provide clinical benefits in breast reconstruction but have been associated with increased postoperative complications, most frequently seromas. Fenestration of the ADM before insertion into the reconstructed breast may reduce the incidence of postoperative complications. In this retrospective analysis, postoperative complications were assessed after breast reconstruction with or without fenestrated ADMs. Patients who underwent immediate 2-staged implant breast reconstructions using ADM at a single center were assessed. The number of reconstructed breasts was stratified by ADM fenestration status and ADM type. The incidence of seroma, infection, extrusion, and explantation, and cosmetic score, was compared within the 2 stratified groups. A multivariable regression was performed to identify independent risk factors associated with these complications and aesthetic outcome. In total, data from 450 patients who had 603 breast reconstructions using either AlloDerm or FlexHD demonstrated a significantly higher incidence of seroma with nonfenestrated ADMs (20%) versus fenestrated ADMs (11%; P = 0.0098). Rates of infection and explantation, and cosmetic score, were not influenced by fenestration status...Continue Reading

References

Dec 22, 2011·Plastic and Reconstructive Surgery·John Y S KimVinay Rawlani
May 1, 2012·Plastic and Reconstructive Surgery·Katie E WeichmanNolan S Karp
May 3, 2013·Annals of Plastic Surgery·Daniel Z LiuOtway Louie
Jun 22, 2013·Annals of Plastic Surgery·Brett F MichelottiJohn Potochny
Oct 28, 2014·Plastic and Reconstructive Surgery·Jenna B MartinGarrett A Wirth
May 15, 2015·Plastic and Reconstructive Surgery. Global Open·Ahmed M S IbrahimSamuel J Lin
Jun 20, 2015·Plastic and Reconstructive Surgery·Donald S MowldsGarrett A Wirth

❮ Previous
Next ❯

Citations

May 18, 2016·Plastic Surgery International·Jessica F RoseWarren A Ellsworth Iv
Feb 15, 2017·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Marek KaweckiAleksandra Kasperczyk
Jul 28, 2018·Aesthetic Surgery Journal·Michael ScheflanTanir M Allweis
Jul 31, 2018·Annals of Plastic Surgery·Adi Maisel LotanMichael Scheflan
Jan 10, 2020·Plastic and Reconstructive Surgery·Tyler SafranTassos Dionisopoulos
Oct 25, 2017·Plastic and Reconstructive Surgery·John Y S Kim, Alexei S Mlodinow
Apr 3, 2020·British Journal of Hospital Medicine·F Bassetto, L Pandis
Sep 30, 2017·Current Treatment Options in Infectious Diseases·Margaret A OlsenIda K Fox
Mar 30, 2020·Plastic and Reconstructive Surgery·Tyler SafranTassos Dionisopoulos
Dec 7, 2018·Journal of the European Academy of Dermatology and Venereology : JEADV·C Chocarro-WronaJ A Marchal
Jun 8, 2018·Plastic and Reconstructive Surgery. Global Open·Keyianoosh Z PaydarDonald S Mowlds
Mar 19, 2019·Plastic and Reconstructive Surgery. Global Open·Elspeth J R Hill, Donald W Buck
Jul 25, 2019·Plastic and Reconstructive Surgery. Global Open·Maurice Y Nahabedian
Feb 11, 2021·Plastic and Reconstructive Surgery. Global Open·Meghan C McCulloughMark Tan
Nov 30, 2020·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Anna LuanRahim S Nazerali

❮ Previous
Next ❯

Software Mentioned

AlloDerm
FlexHD
SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.