PMID: 19920390Nov 19, 2009Paper

Incidence of taste disorder associated with cancer patients undergoing chemotherapy on an ambulatory basis

Gan to kagaku ryoho. Cancer & chemotherapy
Shiho SugawaraMamoru Adachi

Abstract

Taste disorders are a common complaint among cancer patients undergoing chemotherapy on an ambulatory basis. We conducted a survey on the incidence of such disorders among 74 patients, and 45.95% (34 of 74 patients) developed taste disorders. When stratified by medication into a regimen including 5-FU and one including taxanes, taste disorders were found in 59.0% (23 of 39 patients) of the former and 60.0% (9 of 15) of the latter. The survey also included the effects of taste disorders on patients appetites. Both regimens led to reduced appetite in a number of these patients (39.1% and 44.4%, respectively). Among patients on the 5-FU-containing regimen, the FOLFOX/FOLFIRI therapy was found to be responsible for loss of appetite. Regarding change in tastes, many patients stated that the medication dulled their taste sensation except for bitterness; their capacity to sense intensity of taste remained unchanged. It was found that acute taste disorders develop frequently among patients on a high dosage of 5-FU or a taxane-containing regimen.

Related Concepts

Related Feeds

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.

Related Papers

Annals of Oncology : Official Journal of the European Society for Medical Oncology
J CassidyDavid Cunningham
The Breast : Official Journal of the European Society of Mastology
Clifford HudisChau Dang
Annals of Oncology : Official Journal of the European Society for Medical Oncology
F NolèA Goldhirsch
Farmacia hospitalaria : órgano oficial de expresión científica de la Sociedad Española de Farmacia Hospitalaria
F Ferriols LisartJ Magraner Gil
© 2022 Meta ULC. All rights reserved