Incidence, outcome, and risk factors for postoperative pulmonary complications in head and neck cancer surgery patients with free flap reconstructions

Journal of Clinical Anesthesia
Daniela DamianTetsuro Sakai

Abstract

Postoperative pulmonary complications (PPCs) are significant problems in patients undergoing radical head and neck cancer surgery with free flap reconstruction. The objective of the study was to identify the incidence, outcome, and risk factors for PPCs We hypothesized that preoperative pulmonary disease and amount of fluid administered during the surgery would be associated with PPCs. A retrospective clinical observational study. A large academic institution. A total of 110 patients who underwent head and neck cancer surgery with microvascular free flap reconstruction between January 1, 2005 and December 31, 2011. No study interventions were performed. PPCs including pulmonary edema, pneumonia, and acute respiratory distress syndrome were clinically diagnosed. Perioperative parameters and outcomes among patients with and without PPCs were compared. Factors predictive of PPCs were identified with univariate and multiple logistic regression analyses. The incidence of PPCs was 32.7% (36 patients): pulmonary edema in 23.6% (26) and pneumonia in 9.1% (10). No acute respiratory distress syndrome was found. Inhospital mortality was 1.8% (2). No difference was found in survival between the patients with PPCs and those without (1 year ...Continue Reading

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Citations

Mar 16, 2012·Oral Oncology·Joakim JohnsonCaterina Finizia
Jan 25, 2017·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Carolyn L MulveyJason G Newman
Jun 13, 2017·Current Opinion in Otolaryngology & Head and Neck Surgery·Michael R Kinzinger, Arnaud F Bewley
Mar 6, 2019·BMC Anesthesiology·Lin ChenDaqing Ma
Sep 26, 2019·Otolaryngologic Clinics of North America·Douglas M WorrallBrett A Miles
Jul 20, 2020·International Journal of Oral and Maxillofacial Surgery·L M ShawC L Granger
Feb 22, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Francisco Valdez LimaGerson Cipriano Junior
Jan 6, 2021·Journal of Healthcare Quality Research·E Montero RuizL Montes-Jovellar González
Jun 4, 2021·The Journal of Craniofacial Surgery·Maria ChiccoHsu-Tang Cheng
Jul 7, 2021·Head & Neck·Konagalla Karthik, Muthuswamy Dhiwakar
May 26, 2018·Journal of Clinical Anesthesia·Gildasio S De Oliveira

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