PMID: 11325210Apr 28, 2001Paper

Incidence rate and management of prostate carcinoma

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
G Sandblom, E Varenhorst

Abstract

The age-standardised incidence of prostate cancer varies more than one hundredfold between the areas with the highest and lowest incidences in the world. In certain areas, in particular the Western countries, the incidence has increased rapidly over the last 20 years. There are several environmental and genetic factors which partly explain these variations, although the incidence probably depends most of all on the extent to which small latent tumours are detected. As the clinical significance of small tumours is uncertain, the value of early diagnosis and early aggressive treatment is controversial. Randomised trials addressing this question have been initiated and will hopefully provide more evidence-based data in a decade from now. Small localised tumours are managed by radical surgery or radiation therapy. In elderly men or men unfit for operation or radiation therapy surveillance is often preferred. For advanced or metastatic prostate cancers androgen deprivation has been the mainstay of treatment since the early 1940s. Recently, several new treatment strategies have evolved but have not yet been introduced into clinical routine.

References

Nov 15, 1977·International Journal of Cancer. Journal International Du Cancer·N BreslowH Tulinius
Oct 17, 1990·Journal of the National Cancer Institute·A L PotoskyJ W Horm
Jun 1, 1988·International Journal of Radiation Oncology, Biology, Physics·G K ZagarsD H Hussey
Oct 6, 1993·Journal of the National Cancer Institute·E GiovannucciW C Willett
Apr 1, 1996·Urology·M I Resnick
Apr 1, 1996·Urology·J E Oesterling
Aug 10, 1996·BMJ : British Medical Journal·A EkbomD Trichopoulos
Feb 12, 1997·JAMA : the Journal of the American Medical Association·J E JohanssonH O Adami
Aug 26, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·P N PostJ W Coebergh
Sep 28, 1998·JAMA : the Journal of the American Medical Association·P C AlbertsenM J Barry
Jan 27, 2000·JAMA : the Journal of the American Medical Association·J L StanfordA L Potosky
Apr 15, 2000·European Urology·F JacobC C Abbou
May 8, 2000·The Journal of Urology·B Guillonneau, G Vallancien
May 29, 2000·Journal of Occupational and Environmental Medicine·S Sharma-WagnerA W Hsing
Jun 7, 2000·The Journal of Urology·M LauferM A Eisenberger
Jun 24, 2000·JAMA : the Journal of the American Medical Association·F J FowlerM J Barry
Nov 9, 2000·BJU International·J WangJ Waxman
Oct 1, 1954·The Journal of Pathology and Bacteriology·L M FRANKS
Jan 4, 2006·Proceedings·J D McConnell

❮ Previous
Next ❯

Citations

Oct 4, 2003·Clinical Oncology : a Journal of the Royal College of Radiologists·L Potters
Feb 3, 2004·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Ryoichi KizuKazuichi Hayakawai
May 18, 2005·Clinics in Dermatology·Erich Vargas-DíezJesus Fernández-Herrera
Jan 30, 2004·Cancer Immunology, Immunotherapy : CII·Alexander FossåErlend B Smeland

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.