Incidental calcifying fibrous tumor of the stomach presenting as a polyp

Pathology International
Gülsüm Ozlem ElpekMehmet Ogüs

Abstract

Calcifying fibrous tumor (CFT) is an uncommon lesion of uncertain cause and pathogenesis that has a unique histological appearance. These lesions are described mainly in the subcutaneous or deep soft tissues, followed by subserosal locations. Intrinsic visceral CFT is extremely rare. Herein is described a rare case of CFT that involved the gastric wall, along with a review of the literature. An incidental small polypoid lesion was excised during urgent surgery for penetrating injury at the lesser curvature in a 25-year-old man, previously healthy. The lesion was a well-demarcated, small (10 mm) tumor that occupied the submucosa. The characteristic histopathological features and the presence of spindle cells that express factor XIIIa allowed a diagnosis of CFT to be made. The present case and the review revealed that, despite their frequent subperitoneal location, intra-abdominal CFT might present as intrinsic visceral lesions and might be found incidentally. These lesions tend to be smaller when compared to their symptomatic counterparts. The diffuse factor XIIIa expression in CFT might be useful to differentiate this entity from other intra-abdominal soft-tissue tumors in problematic cases. Although rarity of intrinsic viscera...Continue Reading

References

Aug 1, 1989·The American Journal of Surgical Pathology·D M EnglandM J McCarthy
May 1, 1993·The American Journal of Surgical Pathology·J F FetschJ M Meis
Apr 1, 1997·The American Journal of Surgical Pathology·T S EmoryL H Sobin
Aug 1, 1997·Histopathology·L KocovaM Zamecnik
Dec 31, 1997·Pathology International·M ZámecníkL Veselý
Mar 17, 1999·The American Journal of Surgical Pathology·J Van DorpeR Sciot
Mar 25, 2000·Histopathology·M ZámecnikM Sulc
Jun 5, 2001·The British Journal of Radiology·F EftekhariB A Czerniak
Aug 16, 2001·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·K A HillP M Chou
Sep 17, 2002·International Journal of Surgical Pathology·Alessandra F NascimentoChristopher D M Fletcher
Jun 24, 2003·American Journal of Clinical Pathology·Karl T Chen
Nov 8, 2003·World Journal of Gastroenterology : WJG·Dan WuHan-Ting Lin
Dec 12, 2003·The Annals of Thoracic Surgery·Ahlem AmmarTarek Kilani
Mar 31, 2004·Histopathology·K DelbecqueL de Leval

❮ Previous
Next ❯

Citations

Nov 9, 2010·Annales de pathologie·Sameh EllouzeTahia Boudawara
Sep 19, 2009·Gastroentérologie Clinique Et Biologique·G GauchotteK Montagne
Mar 18, 2008·Gastroentérologie Clinique Et Biologique·D ChatelainH Sevestre
Mar 8, 2008·Annals of Diagnostic Pathology·Patrick EmanuelNoam Harpaz
Jul 1, 2015·Archives of Pathology & Laboratory Medicine·Brent K Larson, Deepti Dhall
Feb 6, 2017·Human Pathology·Maryam Kherad PezhouhLysandra Voltaggio
Jul 14, 2012·Journal of the Korean Surgical Society·Kyu Yun JangChan Young Kim
Jun 27, 2007·Advances in Anatomic Pathology·Richard KirschRobert Riddell
Dec 14, 2018·Experimental and Therapeutic Medicine·Shan TianWeiguo Dong
May 20, 2016·Medicine·Angeliki ChortiAntonios Michalopoulos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The American Journal of Surgical Pathology
J F FetschJ M Meis
Annals of Diagnostic Pathology
Patrick EmanuelNoam Harpaz
© 2022 Meta ULC. All rights reserved