Incidental Findings on Brain Magnetic Resonance Imaging in Preterm Infants

Neonatology
Ashok BuchiboyinaSanjay Patole

Abstract

In recent years, many neonatal intensive care units have adopted the practice of routinely performing brain magnetic resonance imaging (MRI) of extremely preterm (EP) infants at term-equivalent age (TEA). This practice may result in increased identification of incidental findings (IF). To determine the prevalence and clinical significance of incidental findings on routine MRI of EP infants. We retrospectively reviewed findings on routine brain MRI on 165 EP infants at TEA (gestation < 28 weeks) admitted between June 2015 and December 2017. Incidental findings were detected in 16/165 (9.7%) infants. This included 9 cases that were clinically significant: 7 (with upper spinal cord abnormalities in 3, a choroid plexus lesion in 1, a pituitary abnormality in 1, and cerebral aqueduct narrowing in 2) required diagnostic intervention, and 2 (1 with an extramedullary arachnoid cyst and 1 with endolymphatic sac dilatation with a hypoplastic cochlear nerve) required diagnostic and therapeutic interventions. The incidental findings in the other 7 cases (a venous anomaly in 2, corpus callosum dysgenesis in 1, an absent septum pellucidum in 2, a frontal scalp mass in 1, and a nasal septum cyst in 1) were not clinically significant. Incident...Continue Reading

References

Jan 1, 1997·Nature Genetics·P R ReillyS H Holtzman
Aug 10, 2000·The New England Journal of Medicine·N S WoodA R Wilkinson
Oct 27, 2004·Journal of Magnetic Resonance Imaging : JMRI·Judy IllesScott W Atlas
Apr 9, 2005·Early Human Development·T Michael O'SheaOlaf Dammann
Aug 18, 2006·The New England Journal of Medicine·Lianne J WoodwardTerrie E Inder
Jun 13, 2008·The Journal of Law, Medicine & Ethics : a Journal of the American Society of Law, Medicine & Ethics·Benjamin S Wilfond, Katherine J Carpenter
Aug 19, 2009·BMJ : British Medical Journal·Zoe MorrisRustam Al-Shahi Salman
Sep 30, 2010·Archives of Internal Medicine·Nicholas M OrmeSusan M Wolf
May 7, 2016·Archives of Disease in Childhood. Fetal and Neonatal Edition·Mariya MalovaLuca Antonio Ramenghi
Oct 11, 2017·Archives of Disease in Childhood. Fetal and Neonatal Edition·A David EdwardsUNKNOWN ePrime Investigators

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Archives of Disease in Childhood. Fetal and Neonatal Edition
Mariya MalovaLuca Antonio Ramenghi
Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
D PugashM Demos
© 2022 Meta ULC. All rights reserved