Incidental thyroid carcinoma in patients with Graves' disease

American Journal of Surgery
Roy Phitayakorn, Christopher R McHenry

Abstract

The clinical significance of incidental thyroid carcinoma in patients with Graves' disease is uncertain. The prevalence of incidental thyroid carcinoma was determined in patients with Graves' disease who underwent surgery from 1990 to 2007 and was compared with patients with nontoxic nodular goiter or toxic multinodular goiter who underwent surgery during the same time period. Of the 93 patients who underwent thyroidectomy for Graves' disease, 2 patients (2.2%) had an incidental papillary carcinoma: .4 and .5 cm in size. Neither patient developed recurrent disease after 3 and 13 years of follow-up evaluation. The prevalence of incidental thyroid cancer was 3.6% and 6.2% in patients with nontoxic nodular goiter and toxic multinodular goiter, respectively (P = not significant). The prevalence of incidental thyroid carcinoma in patients with Graves' disease is comparable with patients with nontoxic or toxic goiter. Incidental thyroid carcinomas in patients with Graves' disease were papillary microcarcinomas of no clinical consequence.

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Citations

Jun 19, 2009·Thyroid : Official Journal of the American Thyroid Association·Maria AlevizakiMeletios-Athanassios Dimopoulos
Jun 22, 2013·Thyroid : Official Journal of the American Thyroid Association·Georgios BoutziosTheodore Karatzas
Apr 8, 2014·Annals of African Medicine·Garba H YunusaAnita Brink
Jul 26, 2011·Annales d'endocrinologie·J-L WémeauL Leenhardt
Aug 26, 2014·Surgery·Jessica PreeceJonathan Serpell
Dec 25, 2009·World Journal of Surgery·Scott M Wilhelm, Christopher R McHenry
Oct 30, 2013·World Journal of Surgery·Meng RenLi Yan
Apr 6, 2011·Journal of the American College of Surgeons·David V Feliciano, John D Lyons
Jul 28, 2009·Journal of the American College of Surgeons·Haejin InJennifer E Rosen
Sep 19, 2012·ANZ Journal of Surgery·Jade A U TamateaGoswin Y Meyer-Rochow
Oct 22, 2014·Endocrine Pathology·Shuanzeng WeiVirginia A LiVolsi
Apr 12, 2018·Archives of Endocrinology and Metabolism·Fausto FamaSalvatore Benvenga
Nov 29, 2012·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Roberto NegroKonstantinos A Toulis
Aug 15, 2019·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Poemlarp MekraksakitRaynald Samoa
Mar 10, 2020·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Kiran Varadharajan, Natasha Choudhury
Aug 30, 2019·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Eunice YouRichard J Payne
Sep 19, 2018·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Sena TurkdoganRichard J Payne

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