Incidental discovery of an adrenal mass during radiologic examinations is common. Several recommendations have been made for the management of so-called incidentalomas. It has become clear that not all incidentalomas should be operated, but the criteria for nonoperative treatment have been under continuous debate. In this study 36 operated incidentalomas are presented, and the indications for operative treatment are discussed with a review of the recent literature on the subject. Four pheochromocytomas and three hormonally active cortical adenomas, two producing cortisol and one androgens, were found. In this series there were no malignancies. The operation could have been avoided in most cases, and patients could have been followed up with repeated radiologic examinations. It is suggested that masses smaller than 6 cm in diameter be followed radiologically after 3, 9, and 18 months. Masses between 3 and 6 cm could be further examined using magnetic resonance imaging and fine needle aspiration and then operated if features suggestive of malignancy are found. Masses larger than 6 cm in diameter should be treated operatively.
Prognostic factors in adrenal cortical tumors. A mathematical analysis of clinical and morphologic data
Preclinical Cushing's syndrome in adrenal "incidentalomas": comparison with adrenal Cushing's syndrome
Endocrine abnormalities in patients with adrenal tumours incidentally discovered on computed tomography
Hyperfunctioning and nonhyperfunctioning benign adrenal cortical lesions: characterization and comparison with MR imaging
Evening urinary free corticoids: a screening test in Cushing's syndrome and incidentally discovered adrenal tumours
Diagnosis and treatment of functioning and nonfunctioning adrenocortical neoplasms including incidentalomas
Usefulness of self-efficacy in predicting overexertion during programmed exercise in coronary artery disease
On the prevalence of adrenocortical adenomas in an autopsy material in relation to hypertension and diabetes
Incidental asymptomatic adrenal masses detected by computed tomographic scanning. Is operation required?
Adrenal metastases: CT-guided and MR-thermometry-controlled laser-induced interstitial thermotherapy
Addisonian crisis secondary to bilateral adrenal metastases in rectal carcinoma: report of a rare case and literature review
Diagnostic accuracy of radionuclide imaging using 131I nor-cholesterol or meta-iodobenzylguanidine in patients with hypersecreting or non-hypersecreting adrenal tumours
Does tumor heterogeneity limit the use of the Weiss criteria in the evaluation of adrenocortical tumors?
Differentiation of adrenal tumors in patients with hepatocellular carcinoma: adrenal adenoma versus metastasis
Prevalence of subclinical Cushing's syndrome in 70 patients with adrenal incidentaloma: clinical, biochemical and surgical outcomes
Long-term outcome of adrenalectomy for metastasis resulting from colorectal cancer with other metastatic sites: A report of 3 cases
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