Incidentalomas of the parathyroid gland: multiple presentations, variable function, and review of the literature.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Paulomi ShroffChristopher M Pezzi

Abstract

To present a series of cases of parathyroid incidentalomas and review the related medical literature. The medical records of all patients of one surgeon who underwent unplanned removal of enlarged parathyroid glands found either during a surgical procedure performed for indications other than hyperparathyroidism or by ultrasonography of the thyroid gland between September 1989 and December 2003 were reviewed retrospectively. Clinical and laboratory data-- especially serum calcium and parathyroid hormone (PTH) levels--as well as information on postoperative parathyroid function are reported. Among 421 patients (355 who underwent thyroidectomy and 66 who underwent transhiatal esophagectomy), 5 cases of parathyroid incidentalomas (1.2%) were identified. These incidental parathyroid adenomas were found during thyroidectomy for thyroid cancer in two patients, during esophagectomy for esophageal cancer in one patient (the first such reported case), and during ultrasonography of the neck for evaluation of thyroid nodules in two patients. Of the five patients, three had a normal and one had a slightly increased serum calcium concentration preoperatively; the serum calcium level was not determined preoperatively in the other patient. In...Continue Reading

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Citations

Aug 26, 2006·Nature Clinical Practice. Endocrinology & Metabolism·Karen Koenig, Michael Kleerekoper
Oct 26, 2010·Annales d'endocrinologie·I BenabbadH O El Malki
Dec 18, 2007·American Journal of Surgery·Bassam AbboudRiad Sarkis
May 15, 2015·Ultrasonography·Jin Yong Sung
Jun 29, 2011·Nature Reviews. Endocrinology·Dimitra A Vassiliadi, Stylianos Tsagarakis

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