PMID: 40686Oct 1, 1979

Incipient germ cell tumor in a cryptorchid testis

S DormanG W Leadbetter


A 13-year-old male who had bilateral cryptorchid testes since birth underwent testicular biopsies and subsequent left orchiectomy following a diagnosis of malignant germ cell tumor. No tumor mass was noted although the malignant cells were seen within the seminiferous tubules and the interstitium. Five recorded cases of in-situ or incipient germ cell neoplasms of the testes are reviewed; three were infertile, another had a cryptorchid testis, and the fifth was both infertile and cryptorchid. Two of these patients have developed frank carcinoma, which would suggest that the process represents an early phase of invasive germ cell neoplasia.


Dec 1, 1982·European Journal of Pediatrics·E Hedinger
Jan 1, 1987·International Urology and Nephrology·M HornákD Ondrus
Jun 22, 2005·Virchows Archiv : an International Journal of Pathology·F E von EybenRolf Inge Skotheim
Aug 1, 1988·Journal of Pediatric Surgery·L CoxD Zacks
Aug 19, 2004·The American Journal of Surgical Pathology·John D HenleyThomas M Ulbright
Apr 1, 1994·British Journal of Urology·M C ParkinsonM C Pike
May 1, 1989·British Journal of Urology·H OzenD Remzi
Feb 1, 1987·International Journal of Andrology·H von der MaaseN E Skakkebaek
Aug 1, 1992·Cancer·P Mikulowski, J Oldbring
Jan 1, 1985·Acta Radiologica. Oncology·O Dahl
Sep 1, 1985·The Journal of Urology·A Nilsson, S Nilsson
Dec 1, 1981·The Journal of Urology·F E von EybenC Busch
Mar 1, 1984·The Journal of Urology·K E MufflyP J Gardner


Feb 1, 1976·AJR. American Journal of Roentgenology·M A BatataH Grabstald
Mar 1, 1975·Urology·J M DeCenzo, G W Leadbetter
Sep 9, 1972·Lancet·N E Skakkebaek
Sep 1, 1974·The Journal of Urology·G G GehringD M Woodhead
Feb 1, 1967·Southern Medical Journal·J A Dow, F K Mostofi
Mar 1, 1967·The Journal of Urology·B L Altman, M Malament
Jun 1, 1954·The Journal of Urology·J N ROBINSON, E T ENGLE
Jun 1, 1954·The Journal of Urology·J S GROVE

Related Concepts

Benign Neoplasm of Testis
Neoplasm of Uncertain or Unknown Behavior of Testis
Germ Cell Tumor
Cancer, Embryonal and Mixed
Neoplastic Disease
Inferior Colliculus

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