Incision of the anulus fibrosus induces nerve root morphologic, vascular, and functional changes. An experimental study

Spine
S KayamaS Kikuchi

Abstract

The effects on nerve root structure, vasculature, and function after incision of the adjacent disc was studied in a dog model. To see if only incision of the disc per se is sufficient for inducing similar changes. It is well known that nucleus pulposus will induce nerve root structural and functional changes in experimental situations. In these previous studies, relatively large amounts of nucleus pulposus were applied. The left L7 nerve root was exposed and mobilized in 10 dogs. In five dogs, the adjacent L6-L7 disc was incised, and in five other dogs, the disc was not incised. After 7 days, nerve conduction velocity was recorded, and specimens were obtained for histologic evaluation. The nerve conduction velocity was significantly lower in the incision group (13 +/- 14 m/sec) compared with the nonincision group (73 +/- 5 m/sec). Structural changes of the axons were more pronounced in the incision group, however, the degree and distribution was too limited to fully account for the neurophysiologic reactions observed. There aims were obvious signs of capillary stasis with an increased number and diameter of the intraneural capillaries in the incision group. The present study indicated that incision of the anulus fibrosus is suf...Continue Reading

Citations

Jun 6, 2006·Skeletal Radiology·Jeffrey S Ross
Aug 4, 2004·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Srinivasu KallakuriJohn M Cavanaugh
Feb 14, 2006·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·A Cüneyt OzaktayJames N Weinstein
Nov 2, 2007·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Miho SekiguchiShin-ichi Kikuchi
Jun 23, 2009·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Hideki NagashimaRyota Teshima
Jun 24, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Kazuhide UesugiShin-ichi Konno
Sep 17, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Michel BenoistGilles Hayem
Aug 19, 2004·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Itaru AraiK Olmarker
Feb 5, 2004·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Stover H Snook
Aug 7, 2002·Spine·Yoshihito AokiKjell Olmarker

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