Inclusion of sprints in moderate intensity continuous training leads to muscle oxidative adaptations in trained individuals

Physiological Reports
T P GunnarssonJens Bangsbo

Abstract

This study examined adaptations in muscle oxidative capacity and exercise performance induced by two work- and duration-matched exercise protocols eliciting different muscle metabolic perturbations in trained individuals. Thirteen male subjects ( V ˙ O2 -max 53.5 ± 7.0 mL·kg-1 ·min-1 ) (means ± SD) performed 8 weeks (three sessions/week) of training consisting of 60 min of moderate intensity continuous cycling (157 ± 20 W) either without (C) or with (C+S) inclusion of 30-s sprints (473 ± 79 W) every 10 min. Total work performed during training was matched between groups. Muscle biopsies and arm venous blood were collected before as well as immediately and 2 h after exercise during the first and last training session. Plasma epinephrine and lactate concentrations after the first and last training session were 2-3-fold higher in C+S than in C. After the first and last training session, muscle phosphocreatine and pH were lower (12-25 mmol·kg d.w.-1 and 0.2-0.4 units, respectively) and muscle lactate higher (48-64 mmol·kg d.w.-1 ) in C+S than in C, whereas exercise-induced changes in muscle PGC-1α mRNA levels were similar within- and between-groups. Muscle content of cytochrome c oxidase IV and citrate synthase (CS) increased m...Continue Reading

References

Mar 1, 1976·Acta Physiologica Scandinavica·B SaltinD Gollnick
Jul 1, 1976·Acta Physiologica Scandinavica·J Henriksson, J S Reitman
Jan 1, 1991·Medicine and Science in Sports and Exercise·E F CoyleG W Petrek
Aug 1, 1987·Medicine and Science in Sports and Exercise·I JacobsE Jansson
Apr 1, 1985·Pflügers Archiv : European journal of physiology·H HowaldR Straub
Jan 1, 1973·Journal of Applied Physiology·P D GollnickR E Shepherd
Feb 1, 1982·Clinical Physiology·P D Gollnick, B Saltin
Feb 1, 1994·Journal of Applied Physiology·C Duan, W W Winder
Jun 11, 1998·Journal of Applied Physiology·J D MacDougallK M Smith
Aug 26, 1998·Medicine and Science in Sports and Exercise·A M Jones, J H Doust
Feb 4, 2003·The Journal of Physiology·Henriette PilegaardP Darrell Neufer
Aug 4, 2004·Pflügers Archiv : European journal of physiology·Peter KrustrupJens Bangsbo
Feb 12, 2005·Journal of Applied Physiology·Kirsten A BurgomasterMartin J Gibala
Jul 5, 2007·Proceedings of the National Academy of Sciences of the United States of America·Sibylle JägerBruce M Spiegelman
Dec 13, 2007·American Journal of Physiology. Endocrinology and Metabolism·Lotte LeickHenriette Pilegaard
Apr 18, 2008·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Frédéric N DaussinRuddy Richard
Dec 8, 2009·Proceedings of the National Academy of Sciences of the United States of America·Jessica ChinsomboonZoltan Arany
Feb 9, 2010·Medicine and Science in Sports and Exercise·Nikolai Baastrup NordsborgHenriette Pilegaard
May 5, 2012·Journal of Applied Physiology·T P Gunnarsson, J Bangsbo
Jan 30, 2013·The Journal of Physiology·Martin ThomassenJens Bangsbo
Feb 12, 2013·Cell Metabolism·Brendan Egan, Juleen R Zierath
Jul 26, 2013·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Thomas P GunnarssonJens Bangsbo
Nov 18, 2015·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Cesare GranataDavid J Bishop
Feb 18, 2016·Medicine and Science in Sports and Exercise·Michael NybergJens Bangsbo
Aug 21, 2016·Journal of Applied Physiology·Benjamin F MillerKaryn L Hamilton

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Citations

Nov 7, 2019·International Journal of Sports Physiology and Performance·Nicki Winfield AlmquistBent R Rønnestad
Apr 9, 2020·American Journal of Physiology. Cell Physiology·Thomas P GunnarssonJens Bangsbo
Jul 19, 2019·Medicine and Science in Sports and Exercise·Phillip M BellingerClare Minahan
Nov 6, 2020·American Journal of Physiology. Cell Physiology·Thomas P GunnarssonJens Bangsbo
Oct 29, 2020·Scandinavian Journal of Medicine & Science in Sports·Nicki Winfield AlmquistBent R Rønnestad
Oct 20, 2020·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Thomas P GunnarssonJens Bangsbo
Mar 30, 2021·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Natália Almeida RodriguesFúlvia Barros Manchado-Gobatto
Jun 4, 2021·Medicine and Science in Sports and Exercise·Nicki Winfield AlmquistBent R Rønnestad
Oct 13, 2021·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Bruno Nicanor Mello-SilvaFabrício Boscolo Del Vecchio

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Methods Mentioned

BETA
biopsy
PCR
biopsies
ELISA

Software Mentioned

Image Lab
SigmaPlot

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