Incorporating a Nebulizer System Into High-Flow Nasal Cannula Improves Comfort in Infants With Bronchiolitis

Respiratory Care
Juan Valencia-RamosJuan Arnaez

Abstract

High-flow nasal cannula (HFNC) is increasingly used to provide respiratory support in infants with bronchiolitis. The delivery of aerosol therapy through a jet nebulizer is widely indicated despite its controversial efficacy and poor tolerability. This randomized cross-over study aimed to evaluate the comfort and satisfaction of the delivery of aerosol therapy using a nebulization system integrated into HFNC compared with the standard practice of using a jet nebulizer with a face mask. The COMFORT-Behavior (COMFORT-B) scale, a visual analog scale, and a numeric rating scale were used by health professionals and caregivers to assess subjects' levels of comfort and satisfaction. A total of 113 nebulizations (64 via nebulizer with HFNC; 49 via jet nebulizer) were delivered to the 6 subjects included in the study. Use of the nebulizer with HFNC showed increased comfort and satisfaction during nebulization compared to use of the jet nebulizer, as measured by the COMFORT-B scale, the visual analog scale, and the numeric rating scale, with the following median (interquartile range) scores: 10.7 (7-16) versus 14.5 (10-20) (P = .006), 8.5 (6-10) versus 7 (4-9) (P = .02), and 3.84 (3.61-4.07) versus 1.83 (1.58-2.08) (P < .001), respectiv...Continue Reading

Citations

Apr 23, 2019·Experimental Lung Research·Juan Valencia-RamosSagrario Beltrán
Aug 27, 2019·Pediatric Emergency Care·Larry B Mellick, Juan Gonzalez
Feb 28, 2020·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Atsushi KawaguchiPadmanabhan Ramnarayan
Aug 8, 2019·Emergency Medicine Australasia : EMA·Kylie BakerJohn F Fraser
Aug 19, 2020·Critical Care : the Official Journal of the Critical Care Forum·Jie LiRajiv Dhand
May 16, 2019·Journal of Aerosol Medicine and Pulmonary Drug Delivery·Jonathan DugernierStephan Ehrmann

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