Incorporating economies of scale in the cost estimation in economic evaluation of PCV and HPV vaccination programmes in the Philippines: a game changer?

Cost Effectiveness and Resource Allocation : C/E
Thanthima SuwanthawornkulYot Teerawattananon

Abstract

Many economic evaluations ignore economies of scale in their cost estimation, which means that cost parameters are assumed to have a linear relationship with the level of production. Economies of scale is the situation when the average total cost of producing a product decreases with increasing volume caused by reducing the variable costs due to more efficient operation. This study investigates the significance of applying the economies of scale concept: the saving in costs gained by an increased level of production in economic evaluation of pneumococcal conjugate vaccines (PCV) and human papillomavirus (HPV) vaccinations. The fixed and variable costs of providing partial (20% coverage) and universal (100% coverage) vaccination programs in the Philippines were estimated using various methods, including costs of conducting questionnaire survey, focus-group discussion, and analysis of secondary data. Costing parameters were utilised as inputs for the two economic evaluation models for PCV and HPV. Incremental cost-effectiveness ratios (ICERs) and 5-year budget impacts with and without applying economies of scale to the costing parameters for partial and universal coverage were compared in order to determine the effect of these di...Continue Reading

References

Feb 4, 2005·Health Policy and Planning·Benjamin JohnsUNKNOWN WHO-CHOICE
Nov 2, 2005·Journal of Health Services Research & Policy·Nicola CooperAlexander Sutton
Feb 4, 2012·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·David B Brushwood
Feb 6, 2017·Health Research Policy and Systems·Karla Hernandez-VillafuerteSteve Wooding

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