PMID: 15232411Jul 3, 2004Paper

Incorporating group-level exposure information in case-control studies with missing data on dichotomous exposures

Epidemiology
Ulf Strömberg, Jonas Björk

Abstract

In case-control studies with exposure data obtained from interviews, participation is an issue of concern. Use of external group-level exposure information, available for all cases and controls (including nonparticipants), can reduce participation bias and improve precision of effect estimates. Our methodologic investigation was motivated by a population-based case-control study on occupational exposures and leukemia. We assessed exposure using dichotomous data collected in interviews, and also using census data on past and current occupational groups for all subjects. Based on information from a job-exposure database, a group-level probability of exposure was assigned to each subject. We studied the performance of the iterative expectation-maximization method for estimating the odds ratio (OR) by using the individual-level exposure data on the interviewed participants together with the assigned group-level exposure probabilities for the nonparticipants. In each iteration, the expected numbers of exposed and unexposed among the nonparticipating cases and controls were calculated from their assigned exposure probabilities and, for the cases only, from the current OR estimate. We then estimated the OR based on the total (observed...Continue Reading

References

Jan 1, 1992·American Journal of Epidemiology·H BrennerS Greenland
Dec 1, 1988·American Journal of Epidemiology·K C Cain, N E Breslow
Nov 1, 1994·Environmental Health Perspectives·W NavidiJ Peters
Mar 26, 1998·American Journal of Industrial Medicine·T KauppinenE Pukkala
Mar 11, 2000·Occupational and Environmental Medicine·T KauppinenM Kogevinas
Aug 24, 2000·Epidemiology·F NybergG Pershagen
Mar 7, 2002·Epidemiology·Sara H OlsonNoel S Weiss
Mar 27, 2002·International Journal of Epidemiology·Jonas Björk, Ulf Strömberg
Mar 27, 2002·International Journal of Epidemiology·Thomas Webster
Jul 3, 2002·Epidemiology·Jonas Björk, Ulf Strömberg
Dec 5, 2002·Journal of Clinical Epidemiology·Lorenzo RichiardiFranco Merletti

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Citations

Apr 15, 2011·Epidemiology·Sebastien Haneuse, Scott Bartell
Nov 9, 2007·Environmental Health : a Global Access Science Source·Anna OudinUlf Strömberg
Feb 1, 2008·Journal of the Royal Statistical Society. Series B, Statistical Methodology·Sebastien J-P A Haneuse, Jonathan C Wakefield

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