PMID: 1278Jan 2, 1976

Incorporation of (1-14C)palmitoyl-CoA into phosphatidylcholine by plasma membranes of rat submaxillary glands in vitro

European Journal of Biochemistry
M S Nijjar, E T Pritchard


1. On incubation with the isolated rat submaxillary gland plasma membranes, [1-14C]palmitoyl-CoA was incorporated mainly into phosphatidylcholine and hydrolysed to [1-14C]palmitic acid and CoASH. 2. The addition of lysophosphatidylcholine enhanced the incorporation into phosphatidylcholine and lowered the hydrolysis of palmitoyl-CoA markedly. 3. In the presence of lysophosphatidylcholine, palmitoyl-CoA incorporation into phosphatidylcholine was maximum at 0.1 mM palmitoyl-CoA, 0.5 mM lysophosphatidylcholine and between pH 7.0 and 9.0. 4. The incorporation into phosphatidylcholine was stimulated by Na+, K+ and K-, inhibited by Ca2+ and Mg2+ and unaffected by sodium deoxycholate and ATP. 5. Epinephrine inhibited the incorporation of palmitoyl-CoA into phosphatidylcholine in the presence or absence of ATP, the inhibition being more in the presence of ATP than in its absence. Dibutyryl adenosine 3':5'-monophosphate mimicked the inhibitory effect of epinephrine.


Jan 1, 1969·Pflügers Archiv : European journal of physiology·A S Ridderstap, S L Bonting
Feb 2, 1971·Biochimica Et Biophysica Acta·J D Newkirk, M Waite
Feb 18, 1972·Science·S J Singer, G L Nicolson
Mar 23, 1972·Biochimica Et Biophysica Acta·G E de CingolaniL L van Deenen
Mar 1, 1974·Canadian Journal of Biochemistry·V K Murthy, G Steiner
Sep 6, 1974·Biochimica Et Biophysica Acta·W RenooijL L van Deenen
Dec 1, 1972·Archives of Oral Biology·M S Nijjar, E T Pritchard
Jul 14, 1966·Annals of the New York Academy of Sciences·L L van Deenen
Aug 1, 1971·The Biochemical Journal·J D Wright, C Green
Aug 22, 1970·Nature·A R PooleJ A Lucy
Jun 1, 1970·The Biochemical Journal·P V SubbaiahJ Ganguly
Oct 1, 1968·The Journal of Cell Biology·Y SteinO Stein
Jan 1, 1964·The Biochemical Journal·G R Webster, R J Alpern
Dec 5, 1967·Biochimica Et Biophysica Acta·H van den BoschL L van Deenen

Related Concepts

Adenosine Triphosphate, Chromium Ammonium Salt
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