Increase in diameters of vasospastic intracranial arteries by intraarterial papaverine administration

Journal of Neurosurgery
J M MilburnR G Dacey

Abstract

This study was conducted to determine if there is a change in intracranial arterial diameters after papaverine infusion for vasospasm and to determine whether the change occurs in proximal, intermediate, and distal arteries. The authors measured arterial diameters retrospectively in all patients who received intraarterial papaverine for treatment of vasospasm between November 1992 and August 1995. Patients who received papaverine in the same session with or following angioplasty were excluded. Measurements were made in a blinded manner with the aid of a magnification loupe at 12 predetermined sites on each angiogram before and after papaverine infusion. Eighty-one treatments in 34 patients were included. Angiograms obtained at the time of presentation with subarachnoid hemorrhage (SAH) were examined in 26 of the 34 patients. Nine carotid territories visualized by repeated angiography on the day after infusion were examined to determine the duration of the papaverine effect. In all treatment groups an increase was found in the average arterial diameters ranging from 2.8 to 73.9%, with a mean increase of 26.5%. Increases in diameter were observed in proximal, intermediate, and distal arteries. The timing of treatments ranged from...Continue Reading

References

Feb 1, 1978·Journal of Neurosurgery·B WeirC Rothberg
Oct 1, 1990·Neurosurgery·T NakagomiT Sasaki
Jan 1, 1988·Annual Review of Pharmacology and Toxicology·J A Bevan, R D Bevan
Nov 1, 1974·Biochemical Pharmacology·C Lugnier, J C Stoclet
Jan 1, 1970·Acta Radiologica: Diagnosis·T O Gabrielsen, T Greitz
Jan 1, 1966·Acta Radiologica: Diagnosis·P B Wollschlaeger, G Wollschlaeger
Dec 1, 1983·Annals of Neurology·R C HerosV Varsos
Jan 1, 1965·Journal of Neurosurgery·J M ALLCOCK, C G DRAKE

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Citations

Jan 29, 2005·Current Treatment Options in Neurology·Alejandro A Rabinstein, Eelco F M Wijdicks
Oct 31, 2007·Neurocritical Care·Kelly GoodsonJulio A Chalela
Jan 5, 2012·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·M Kamran Athar, Joshua M Levine
Aug 21, 2007·Critical Care : the Official Journal of the Critical Care Forum·Salah G Keyrouz, Michael N Diringer
May 18, 2005·NeuroRx : the Journal of the American Society for Experimental NeuroTherapeutics·Jawad F KirmaniAdnan I Qureshi
Oct 13, 2006·Neurosurgical Focus·Christina M SayamaWilliam T Couldwell
Oct 13, 2006·Neurosurgical Focus·Stefan A MindeaH Hunt Batjer
Dec 14, 2006·Neurological Research·Jonathan L BrismanDavid W Newell
Jan 31, 2013·Journal of Neurointerventional Surgery·Joseph SerroneAndrew J Ringer
Jun 9, 2006·Neurological Research·Altay Sencer, Talat Kiriş
Jul 6, 2014·Neurosurgery Clinics of North America·Christopher D Baggott, Beverley Aagaard-Kienitz
Oct 16, 2007·Annales Françaises D'anesthèsie Et De Rèanimation·L AbdennourL Puybasset
Jun 16, 2007·Journal of the Neurological Sciences·Ricardo J KomotarE Sander Connolly
Jun 2, 2000·Journal of Vascular and Interventional Radiology : JVIR·T P Smith, D S Enterline
Jan 13, 2005·The Journal of Pediatrics·M Pamela Griffin, Mir S Siadaty
Jan 24, 2006·Surgical Neurology·Daniel Monte-Serrat PrevedelloJoão Cândido Araújo
Feb 8, 2005·Neurosurgery Clinics of North America·Ricardo A HanelL Nelson Hopkins
Apr 15, 2005·Neurological Research·Osamu IgarashiYasuo Iwasaki
Dec 3, 2014·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Gerasimos BaltsaviasAnton Valavanis
Jan 27, 2005·Neurosurgery·Kazuhiro TanakaEiji Kohmura
Nov 24, 1999·Critical Care Clinics·D W NewellH R Winn
Jun 10, 2003·Critical Care Medicine·Michael N Diringer
Mar 10, 2001·Stroke; a Journal of Cerebral Circulation·M NakajimaT Ohmoto
Mar 22, 2003·Stroke; a Journal of Cerebral Circulation·Miriam M TreggiariNicolas de Tribolet
Feb 7, 2001·Stroke; a Journal of Cerebral Circulation·P VajkoczyP Schmiedek
Oct 22, 2009·Journal of Korean Neurosurgical Society·Jong Hoon KimSoo Hyun Hwang

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