PMID: 6377985Jan 1, 1984

Increase in functional residual capacity induced by positive end-expiratory pressure. Prediction using the thoracopulmonary pressure curve

Annales Françaises D'anesthèsie Et De Rèanimation
D MatamisP Rieuf


Prediction of FRC using a respiratory P-V curve (2 1 syringe method) has been tested in eight patients with normal lungs and in 12 ARDS patients. FRC was measured using nitrogen dilution technique with a closed circuit. Correlation between measured and predicted FRC was excellent, especially when the expiratory limb of the P-V curve was used (r = 0.92, in patients with pulmonary edema, and r = 0,97 when patients were evaluated after a few weeks). PEEP induced increase in FRC was larger between 10 and 20 cmH2O than between 0 and 10 cmH2O. As expected, Qs/Qt decrease was correlated with the FRC augmentation.


Jun 2, 2005·Current Opinion in Critical Care·Luciano GattinoniPietro Caironi

Related Concepts

Functional Residual Capacity
Lung Volume Measurements
Positive End-Expiratory Pressure
Respiratory Distress Syndrome, Adult
Total Lung Capacity

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