PMID: 6966421Feb 1, 1980Paper

Increase in T gamma lymphocytes in B-cell chronic lymphocytic leukaemia

Scandinavian Journal of Haematology
F LauriaD Catovsky

Abstract

A significant increase in the proportion (mean 38% +/- 9.3 SD) and absolute number of T gamma (suppressor) lymphocytes was observed in 13 patients with chronic lymphocytic leukaemia (CLL) compared with 20 normal controls (mean 19% +/- 6.5). Conversely, the proportion of T mu (helper) lymphocytes was lower in CLL (mean 27% +/- 9.3) than in the controls (mean 40% +/- 4), although the absolute numbers were normal or increased. It is suggested that an imbalance of T-lymphocyte subsets controlling B-lymphocyte differentiation may be relevant in the pathogenesis of CLL or some of its associated features.

References

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Citations

May 1, 1986·American Journal of Hematology·R T Perri, N E Kay
Oct 1, 1983·Scandinavian Journal of Haematology·R FoaD Catovsky
Oct 1, 1982·Scandinavian Journal of Haematology·C P Worman, J C Cawley
Feb 1, 1984·American Journal of Hematology·M A Socinski, W B Ershler
Dec 1, 1980·British Journal of Haematology·R FoaD A Galton
Feb 1, 1981·Scandinavian Journal of Haematology·F LauriaS Tura
Dec 1, 1981·British Journal of Haematology·M M Oken, N E Kay
Oct 15, 1982·Klinische Wochenschrift·G SieberH Rühl
Jan 1, 1982·British Journal of Haematology·C A WhelanS R McCann
Jul 1, 1983·Journal of Clinical Immunology·C D PlatsoucasB D Clarkson
Aug 7, 2001·Reviews in Clinical and Experimental Hematology·E OrsiniR Foa
Nov 8, 2001·Leukemia & Lymphoma·R Aboul-NasrM Albitar
Dec 1, 1981·British Journal of Haematology·E MatutesD Catovsky
Nov 1, 1982·Scandinavian Journal of Haematology·D CatovskyM F Greaves
Jun 1, 1987·Baillière's Clinical Haematology·T J Hamblin
Aug 1, 1985·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·B PauleJ P Le Bourgeois

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