PMID: 8961877Dec 1, 1996Paper

Increase of melanocytic nevus counts in children during 5 years of follow-up and analysis of associated factors

Archives of Dermatology
Heike LutherM Segerling

Abstract

To investigate nevus development in childhood and to examine causative related factors such as pigment phenotype and the role of sun exposure in the development of melanocytic nevi. Nevus counts were performed in kindergarteners (n = 866) before the age of 7 years and again 5 years later (n = 377). Eligible for analysis were 357 children who were examined twice. Possible related factors were searched for by standardized interviews with parents. The mean number of nevi measuring 1 mm or more was 9 in the first examination and the number measuring 2 mm or more, 4. Five years later, the mean number of nevi measuring 1 mm or more was 40 and the number measuring 2 mm or more was 16. Children with poor sun tolerance had statistically significant more nevi (relative risk, 3.7;95% confidence interval, 1.9-7.2). The presence of freckles was a strong predictor for a high increase of melanocytic nevi (relative risk, 2.1; 95% confidence interval, 1.3-3.3). The number of days per year with intensive solar exposure was an independent prognostic factor. The relative risk for the development of melanocytic nevi was increased by a factor of 1.6 in children who had more than 21 days of intensive sun exposure per year (95% confidence interval, 1....Continue Reading

Citations

Feb 18, 2009·Archives of Dermatology·Lori A CraneJoseph G Morelli
Sep 23, 2009·Archives of Dermatology·Jenny AalborgLori A Crane
Sep 5, 2002·International Journal of Cancer. Journal International Du Cancer·Paolo CarliUNKNOWN Oncology Cooperative Group of the Italian Group for Epidemiologic Research in Dermatology (GISED)
Jan 1, 2003·Journal of Clinical Epidemiology·Madeleine DulonEckard W Breitbart
Nov 13, 2008·American Journal of Epidemiology·Susan A OliveriaAllan C Halpern
Sep 22, 2012·Pediatric Dermatology·Marie-Florence de MaleissyeEmmanuel Mahé
Feb 5, 2009·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Kelly J PettijohnLori A Crane
Apr 9, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·G SeveriUNKNOWN European Organization for Research Treatment of Cancer (EORTC) Melanoma Cooperative Group
Apr 12, 2002·American Journal of Epidemiology·Elizabeth MilneDallas R English
Mar 25, 2014·Dental Clinics of North America·Geoffrey F S LimJoseph M Kist
Jan 13, 2005·International Journal of Cancer. Journal International Du Cancer·Jürgen BauerClaus Garbe
Nov 22, 2011·American Journal of Preventive Medicine·Richard G RoetzheimKristen J Wells
Jun 30, 2010·Journal of the American Academy of Dermatology·Jenny AalborgLori A Crane
Jul 22, 2008·Journal of the European Academy of Dermatology and Venereology : JEADV·Z CsomaJ Olah
Jan 5, 2008·International Journal of Dermatology·Skaidra ValiukevicieneAndreas Stang
Jul 19, 2011·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Axel HauschildUNKNOWN expert group "Melanocytic nevi"
Dec 18, 2009·Journal of the European Academy of Dermatology and Venereology : JEADV·V LichteM Moehrle
Apr 25, 2014·International Journal of Dermatology·Ekramy A El-KhateebSuzan E El-Shiekh
Apr 15, 2003·The Surgical Clinics of North America·Susan M Swetter
Dec 11, 2014·Journal of the European Academy of Dermatology and Venereology : JEADV·S KontautieneS Valiukeviciene
Nov 14, 2008·Orvosi hetilap·Zsanett CsomaJudit Oláh
Jun 21, 2016·Journal of the American Academy of Dermatology·Alon ScopeAllan C Halpern
Apr 23, 2016·International Journal of Cancer. Journal International Du Cancer·Nicholas J TaylorUNKNOWN GEM Study Group
Aug 16, 2016·Pediatric Annals·Rebecca Levy, Irene Lara-Corrales
Aug 5, 1999·Journal of the National Cancer Institute·P AutierA M Eggermont
Oct 14, 2005·Expert Review of Anticancer Therapy·Philippe Autier
Nov 10, 2000·International Journal of Cancer. Journal International Du Cancer·H VainioF Bianchini
Apr 11, 2018·Journal of the European Academy of Dermatology and Venereology : JEADV·A PapakonstantinouE Lazaridou
May 15, 2007·Melanoma Research·Claus Garbe, Thomas K Eigentler
Apr 26, 2005·International Journal of Cancer. Journal International Du Cancer·Jürgen BauerClaus Garbe
Feb 28, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·M SuppaV Del Marmol
Oct 6, 2005·Dermatology : International Journal for Clinical and Investigative Dermatology·E A LaVigneA A Marghoob
Apr 30, 2016·Nature Reviews. Cancer·A Hunter Shain, Boris C Bastian
Jun 13, 2017·Oncogene·W E Damsky, M Bosenberg
Apr 30, 2020·Dermatologic Therapy·Fatma Pelin CengizNahide Onsun
Nov 7, 2001·Clinical and Experimental Dermatology·M Yaar, B A Gilchrest

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.