PMID: 9183495May 1, 1997Paper

Increase of staphylococci in neonatal septicaemia: a fourteen-year study

Acta Paediatrica
J KällmanJ Schollin

Abstract

All cases of neonatal septicaemia during 1981-94 were studied at Orebro Medical Centre Hospital, Sweden. One hundred and thirty-two children fulfilled laboratory and clinical criteria for neonatal septicaemia and were included. Staphylococcus aureus (n = 41), Group B streptococcus (GBS) (n = 32) and coagulase-negative staphylococci (CoNS) (n = 27) were the dominating aetiologies. The annual incidence of septicaemia increased significantly, from 2.3 cases during the first 7-year period to 3.3 per 1000 live births during 1988-94. This increase was caused by S. aureus and CoNS, which mainly affected premature children and had an onset more than 48 h after delivery. GBS, on the other hand, slightly decreased and affected full-term children within 48 h. The overall mortality was 11%. CoNS isolated during the latter 7-year period were more resistant to antibiotics than those isolated during 1981-87; resistance to methicillin increased from 14 to 45% and to gentamicin from 0 to 20%. These changes in aetiology and antibiotic susceptibility should be considered when selecting antibiotic treatment in neonatal septicaemia.

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Citations

Jun 22, 2002·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Maria BjörkqvistJens Schollin
Jun 28, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Scott A McConnellElias J Anaissie
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Apr 29, 2011·BMC Public Health·Anita K M ZaidiJoy E Lawn
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Jun 24, 2010·Clinics in Perinatology·Hammad A GanatraAnita K M Zaidi
Jun 4, 2004·Acta Paediatrica·R A van LingenG J H M Ruijs
Jan 16, 2009·Acta Paediatrica·I Adlerberth, A E Wold
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Aug 15, 2001·Journal of Perinatology : Official Journal of the California Perinatal Association·A Craft, N Finer

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