Increased acid excretion in kidney stone formers with essential hypertension

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Attilio LositoGaetano Ferrara

Abstract

Although several studies have reported that kidney stone disease and hypertension are associated, the link between the two conditions has not been identified. This study investigated urinary excretion of different solutes, particularly citrate and acids, in kidney stone formers and examined their association with high blood pressure. The retrospective study included 234 consecutive subjects, aged 47.0 +/- 15.6, attending our metabolic clinic after episodes of kidney stones. Essential hypertension was present in 82 patients (35.0%). A difference in the urinary excretion of some of the investigated components was found between subjects with normal blood pressure and those with hypertension. The results showed that hypertensive subjects were older and had a higher body mass index (BMI) and serum uric acid. They had a significantly lower urinary pH (5.6 +/- 0.4 versus 6.0 +/- 0.5) and citrate (2.55 +/- 1.36 versus 2.83 +/- 1.65 mmol/24 h), higher titratable acid (38.8 +/- 19.0 versus 26.8 +/- 15.0 mEq/24 h) and ammonium (41.6 +/- 17.6 versus 34.2 +/-12.4 mmol/24 h). Logistic regression analysis with the presence of hypertension as the dependent variable produced a model with the following predictors: age (P < 0.0001), BMI (P = 0.02...Continue Reading

References

May 12, 1990·BMJ : British Medical Journal·F P CappuccioM Mancini
Dec 1, 1988·Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension·M Cirillo, M Laurenzi
Jan 1, 1985·Kidney International·B J MaroniW E Mitch
Sep 1, 1966·The New England Journal of Medicine·P J CannonJ H Laragh
Dec 1, 1983·British Journal of Urology·W G RobertsonA Smith
Jul 1, 1993·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·K SakhaeeC Y Pak
May 1, 1993·The Journal of Clinical Investigation·D C BatlleC Gutterman
Jun 3, 1999·Kidney International·L BorghiA Novarini
Jan 29, 2002·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Andras TislerAlexander G Logan
Apr 26, 2003·Journal of Hypertension·Eoin O'BrienUNKNOWN European Society of Hypertension Working Group on Blood Pressure Monitoring
May 16, 2003·JAMA : the Journal of the American Medical Association·Aram V ChobanianUNKNOWN National High Blood Pressure Education Program Coordinating Committee
Aug 23, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Daniel L GillenElaine M Worcester
Apr 25, 2006·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Eric N TaylorGary C Curhan
Jul 21, 2006·Journal of the American Society of Nephrology : JASN·Andrew MenteAlexander G Logan
Dec 13, 2006·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Eric N Taylor, Gary C Curhan

❮ Previous
Next ❯

Citations

Nov 18, 2011·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Kazuki AkiraTakao Hashimoto
Mar 17, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Baris AfsarTayfun Eyileten
Jun 6, 2009·American Journal of Physiology. Renal Physiology·John H WiessnerNeil S Mandel
Nov 28, 2012·The Urologic Clinics of North America·Herman Singh BaggaMarshall L Stoller
Jul 18, 2014·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Andrea TicinesiTiziana Meschi
Oct 30, 2014·Renal Failure·Huseyin BesirogluEmin Ozbek
May 4, 2016·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Yung-Chin LeeChia-Chu Liu
Jun 5, 2012·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Meng DaiPeiyu Wang
May 18, 2012·Asia-Pacific Journal of Public Health·Ai ZhaoPei Yu Wang
Jul 19, 2018·American Journal of Physiology. Renal Physiology·Danika KruppThomas Remer
Aug 22, 2012·The Journal of Urology·Paul J KokorowskiCaleb P Nelson
Jun 9, 2020·Journal of Atherosclerosis and Thrombosis·Ahmed ArafaUNKNOWN JPHC Study Group
Oct 3, 2020·International Journal of Microbiology·Pratima ShahBasudha Khanal
Jan 21, 2012·Current Opinion in Urology·Jessica N LangeDean G Assimos
Oct 26, 2010·Urology·Yong-June KimSang-Cheol Lee
May 4, 2016·Antimicrobial Agents and Chemotherapy·Guillermo Martín-GutiérrezJesús Blázquez
Jul 22, 2021·Archivio italiano di urologia, andrologia : organo ufficiale [di] Società italiana di ecografia urologica e nefrologica·Elisa CicerelloMario S Mangano

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Domenico RendinaPasquale Strazzullo
JAMA : the Journal of the American Medical Association
Eric N TaylorGary C Curhan
© 2022 Meta ULC. All rights reserved