Increased brainstem volume in panic disorder: a voxel-based morphometric study

Neuroreport
Xenia ProtopopescuD Silbersweig

Abstract

Neurocircuitry models of panic disorder have hypothesized that the panic attack itself stems from loci in the brainstem including the ascending reticular system and respiratory and cardiovascular control centers. Voxel-based morphometry with acobian modulation was used to examine gray matter volume changes in 10 panic disorder patients and 23 healthy controls. The panic disorder patients had a relatively increased gray matter volume in the midbrain and rostral pons of the brainstem. Increased ventral hippocampal and decreased regional prefrontal cortex volumes were also noted at a lower significance threshold. This finding has implications for pathophysiologic models of panic disorder, and provides structural evidence for the role of the brainstem in neurocircuitry models of panic disorder.

References

Feb 1, 1990·Biological Psychiatry·R FontaineR Elie
Jan 1, 1989·The Journal of Neuropsychiatry and Clinical Neurosciences·A OntiverosR Déry
Feb 1, 1989·The American Journal of Psychiatry·J M GormanJ Stein
Jul 1, 1981·European Journal of Cancer & Clinical Oncology·G O Klein, G Klein
Jan 1, 1998·Transplantation Proceedings·M R First
Mar 30, 2000·The American Journal of Psychiatry·J M GormanJ D Coplan
Jun 22, 2000·NeuroImage·J Ashburner, K J Friston
Aug 30, 2000·Psychiatry Research·M VythilingamJ D Bremner
Oct 23, 2002·Human Brain Mapping·Stephen M Smith
Mar 4, 2003·The American Journal of Psychiatry·Guillem MassanaJosé María Mercader
Sep 1, 1981·Immunology Today·J Klein

❮ Previous
Next ❯

Citations

Jun 24, 2008·Journal of Neural Transmission·Kirsten EngelDirk Wedekind
Jun 14, 2012·Journal of Neural Transmission·Thomas DreslerKatharina Domschke
Jul 25, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Lisa M Shin, Israel Liberzon
Jul 2, 2009·Psychiatry and Clinical Neurosciences·Fumi HayanoYoshio Hirayasu
Jun 21, 2011·Psychiatry and Clinical Neurosciences·Akiko FujiwaraYoshio Hirayasu
Nov 22, 2012·Biology of Mood & Anxiety Disorders·Jieun E KimIn Kyoon Lyoo
Mar 23, 2012·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·F G Graeff
Mar 14, 2009·Neural Plasticity·Cristina Marta Del-Ben, Frederico Guilherme Graeff
Aug 19, 2014·Neuroscience and Biobehavioral Reviews·Philip L JohnsonAnantha Shekhar
Oct 4, 2012·Harvard Review of Psychiatry·Larry SandbergBarbara Milrod
Apr 22, 2011·Journal of Clinical Psychopharmacology·Chien-Han Lai
Feb 9, 2010·Expert Review of Neurotherapeutics·Marcele Regine de CarvalhoAntonio Egidio Nardi
Jan 22, 2013·Biological Psychiatry·Richard J MaddockApril M Unruh
Apr 11, 2012·Behavioural Brain Research·J S de AndradeM B Viana
Jul 6, 2010·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Chien-Han LaiYu-Te Wu
Jun 23, 2009·Journal of Affective Disorders·Tsutomu TakahashiNicholas B Allen
Jun 30, 2009·Psychiatry Research·Takeshi AsamiYoshio Hirayasu
Oct 22, 2008·Hand Clinics·Dimitri J AnastakisDavid Mikulis
Jun 25, 2008·Neuroscience and Biobehavioral Reviews·Frederico G Graeff, Cristina M Del-Ben
Apr 18, 2008·Psychiatry Research·Ricardo R UchidaFrederico G Graeff
Dec 27, 2011·NeuroImage·Clas LinnmanDavid Borsook
Nov 16, 2010·Journal of Anxiety Disorders·Oliver TuescherEmily Stern
Mar 31, 2015·European Journal of Pharmacology·Mónica SantosMara Dierssen
Sep 17, 2013·Human Psychopharmacology·Justine Nienke PannekoekNic J A van der Wee
Jun 11, 2015·International Psychogeriatrics·Olivier PotvinHélène Amieva
May 1, 2013·Progress in Neuro-psychopharmacology & Biological Psychiatry·Kyoung-Sae NaHo-Kyoung Yoon
Jan 15, 2013·Progress in Neuro-psychopharmacology & Biological Psychiatry·Borah KimSang-Hyuk Lee
Jul 23, 2013·Journal of Psychiatric Research·Sujung YoonIn Kyoon Lyoo
Jul 29, 2010·The International Journal of Neuropsychopharmacology·Chien-Han Lai, Yuan-Yu Hsu
Jun 19, 2012·Psychiatry Investigation·Murad AtmacaFiliz Koseoglu
Dec 20, 2012·Psychiatry Investigation·Murad AtmacaMuammer Akyol
Jul 13, 2016·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Borwin BandelowPeter Riederer
Jul 21, 2016·Human Brain Mapping·Katharina FeldkerThomas Straube
Oct 4, 2008·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Maria Cecília Freitas FerrariJosé Alexandre S Crippa
Dec 15, 2010·Journal of Psychopharmacology·Eduard MaronJarmo Hietala
May 23, 2009·Journal of Psychopharmacology·G EsquivelE J Griez
Oct 12, 2018·Psychiatry Investigation·Seon-Cheol Park, Yong-Ku Kim

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.