PMID: 8964198Feb 1, 1996Paper

Increased cardiovascular morbidity and mortality in diabetes mellitus: identification of the high risk patient

Diabetes Research and Clinical Practice
H U Janka

Abstract

Cardiovascular diseases are the major cause of morbidity and mortality in the diabetic patient. Acute myocardial infarction carries twice the mortality of that in the general population. Although in the thrombolytic era, in-hospital survival for both diabetic and non-diabetic patients have improved considerably, the overall case fatality rate due to out-of-hospital death is still more than 50%. Screening relates particularly to the systematic search for cardiovascular risk factors and asymptomatic atherosclerosis. The individual risk cannot exactly be described by the level of risk factors alone. Today, diagnosis of preclinical cardiovascular disease can identify the high risk patient for severe cardiovascular events. The presence of asymptomatic or 'preclinical' cardiovascular disease such as left ventricular hypertrophy, peripheral arterial vessel disease, carotid atherosclerosis, autonomic neuropathy, and renal dysfunction carries a markedly increased risk for symptomatic morbidity as well as cardiovascular mortality. The unfavorable connection between autonomic neuropathy and coronary heart disease risk has just recently been reported. Therefore, diabetic patients with existing cardiovascular disease should be investigated ...Continue Reading

References

Apr 1, 1987·The Journal of Clinical Endocrinology and Metabolism·J K KahnA I Vinik
Nov 1, 1993·Diabetic Medicine : a Journal of the British Diabetic Association·W RathmannF A Gries

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Citations

Feb 1, 2003·Diabetes Research and Clinical Practice·Michiaki FukuiToshikazu Yoshikawa
Feb 6, 2004·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Sabine FredersdorfJoachim Weil
Feb 23, 2013·Heart Failure Reviews·Tod A ClarkGrant N Pierce
Feb 18, 2006·The Canadian Journal of Cardiology·Djilali Hanzal, Anique Ducharme
Apr 3, 2010·Biochemical Pharmacology·Chun-Hong ShaoKeshore R Bidasee
Jul 25, 2008·Nature Clinical Practice. Cardiovascular Medicine·Jeanne M Link, James H Caldwell
Sep 28, 2014·European Journal of Applied Physiology·Tim H A SchreuderDick H J Thijssen
Feb 28, 2003·The Journal of Pharmacology and Experimental Therapeutics·Keshore R BidaseeU Deniz Dincer
Nov 26, 2011·Expert Review of Clinical Pharmacology·Kaushik M DesaiLingyun Wu
Mar 2, 2021·Diabetes Research and Clinical Practice·Fengze NieXinhua Hu

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