Increased delta neutrophil index in women with severe preeclampsia

American Journal of Reproductive Immunology : AJRI
Hee Young ChoJa-Young Kwon

Abstract

The pathophysiology of preeclampsia (PE) is believed to be associated with a systemic inflammatory response, but few inflammatory markers are currently available to predict PE. Therefore, the aim of this study was to compare the serum delta neutrophil index (DNI) between normal and preeclamptic women. Sixty-five patients with mild preeclampsia (mPE), 147 patients with severe preeclampsia (sPE), and 163 women with normal pregnancy were included in this study. Maternal laboratory values including DNI were compared among the three groups. The mean DNI was significantly higher in the sPE group, but there was no significant difference between the normal pregnancy group and mPE. The DNI also showed positive correlation with systolic and diastolic blood pressures, mean arterial pressure, proteinuria during 24 hours, proteinuria in dipstick, and ominous symptoms. The serum DNI value was increased in women with severe preeclampsia compared to that in those with normal pregnancy or mild preeclampsia. Further studies are needed to evaluate application of the DNI value as a prognostic marker of preeclampsia.

References

Oct 1, 1995·European Journal of Obstetrics, Gynecology, and Reproductive Biology·I RebeloA Quintanilha
Mar 1, 1997·American Journal of Reproductive Immunology : AJRI·K P Conrad, D F Benyo
Jun 12, 1998·Gynecologic and Obstetric Investigation·S LurieY Tuvbin
Jan 19, 2002·Hypertension·Jan Roar MellembakkenVibeke Videm
Mar 26, 2005·Laboratory Hematology : Official Publication of the International Society for Laboratory Hematology·Neil HarrisAlexander Kratz
May 20, 2009·American Journal of Perinatology·Bernard J CanzoneriYuping Wang
May 28, 2009·Reproduction : the Official Journal of the Society for the Study of Fertility·G J BurtonE Jauniaux
Mar 25, 2010·American Journal of Reproductive Immunology : AJRI·Christopher W G Redman, Ian L Sargent
May 2, 2013·Journal of Leukocyte Biology·Estibalitz Laresgoiti-Servitje
Jul 3, 2013·Physiology·Babbette LaMarcaKedra Wallace
Mar 19, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Emel KurtogluErdal Malatyalioglu
Sep 13, 2015·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Keziban DoğanMurat Ekin
Feb 6, 2016·Clinical Science·Ashlyn C HarmonBabbette LaMarca
Mar 10, 2016·Pregnancy Hypertension·Salih SerinHakan Kıran

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Citations

May 6, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Nihal Şahin UysalAykan Yücel
Jul 14, 2021·Zeitschrift für Geburtshilfe und Neonatologie·Gökhan KarakoçAykan Yucel
Sep 18, 2021·The Journal of Obstetrics and Gynaecology Research·Hasan EroğluAykan Yücel

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