Increased dietary cholesterol does not increase plasma low density lipoprotein when accompanied by an energy-restricted diet and weight loss.

European Journal of Nutrition
Nicola L HarmanBruce A Griffin

Abstract

Diets enriched with dietary cholesterol, frequently from eggs, have been shown to produce a small but variable increase in plasma low density lipoprotein (LDL) cholesterol. There is evidence to suggest that energy-restricted diets, that may contain a relatively high proportion of fat and cholesterol, can attenuate the cholesterol-raising effect of dietary cholesterol on plasma LDL. To determine the combined effects of increased dietary cholesterol and weight loss produced by energy restriction on plasma LDL cholesterol and lipoproteins. A randomized, controlled, parallel study was performed in two groups of free-living volunteers on an energy-restricted diet for 12 weeks, one group was instructed to consume two eggs a day (n = 24), the other, to exclude eggs (n = 21). Dietary advice on energy restriction was based on the British Heart Foundation guidelines on how to lose weight for men and women. Energy intake fell by 25 and 29% in the egg-fed and non-egg-fed groups, resulting in a moderate weight loss of 3.4 kg (P < 0.05) and 4.4 kg (P < 0.05), respectively. The daily intake of dietary cholesterol increased significantly in the egg-fed group from 278 to 582 mg after 6 weeks. The concentration of plasma LDL cholesterol decrease...Continue Reading

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Citations

Aug 5, 2010·Current Atherosclerosis Reports·Maria Luz Fernandez, Mariana Calle
Oct 1, 2010·The British Journal of Nutrition·Krista A VaradyBenoît Lamarche
May 12, 2011·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Brenda Lee Simas PortoMarcone Augusto Leal de Oliveira
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Mar 30, 2018·Nutrients·Christopher N Blesso, Maria Luz Fernandez
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Nov 1, 2011·Current Opinion in Clinical Nutrition and Metabolic Care·Maria L Fernandez
Nov 8, 2017·Journal of the American College of Nutrition·Mohammad Hossein RouhaniFahimeh Haghighatdoost
Sep 28, 2017·European Journal of Clinical Nutrition·N R W GeikerA Astrup
Mar 7, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Marta Czarnowska-KujawskaMarta Kasińska
Nov 16, 2010·The Canadian Journal of Cardiology·J David SpenceJean Davignon

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