Increased epicardial fat is independently associated with the presence and chronicity of atrial fibrillation and radiofrequency ablation outcome

European Radiology
Jadranka StojanovskaHakan Oral

Abstract

To determine whether intrathoracic fat volumes are associated with presence and chronicity of atrial fibrillation (AF) and radiofrequency ablation (RFA) treatment outcome. IRB approval was obtained and patient consent was waived for this HIPAA-compliant retrospective study. 169 patients with AF (75 non-paroxysmal and 94 paroxysmal) and 62 control patients underwent cardiac CT examination. Extrapericardial (EPFV) and epicardial fat volumes (EFV) were measured on CT, the sum of which is the total intrathoracic fat volume. Associations between these three fat volumes and presence and chronicity of AF, and outcome after RFA, were evaluated using logistic regression analysis. EFV was significantly associated with presence [OR 1.01 (95 % CI 1.003-1.03), p = 0.01], chronicity of AF [1.008 (1.001-1.020), p = 0.03] and AF recurrence after RFA [1.009 (1.001-1.01), p = 0.02] after adjustment for age, gender and BMI. Patients with a larger EFV had a shorter time to AF recurrence (p = 0.017) and a higher rate of recurrence (54 % vs 46 %) (p = 0.002) after RFA. EPFV had no significant associations. Increased epicardial fat is associated with the presence and chronicity of AF, a higher probability of AF recurrence after RFA and a shorter AF-f...Continue Reading

References

Jul 1, 1982·The American Journal of Clinical Nutrition·G A BorkanJ E Silbert
Sep 3, 1998·The New England Journal of Medicine·M HaïssaguerreJ Clémenty
Mar 10, 2001·The Medical Clinics of North America·F Pelosi, F Morady
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
May 29, 2003·Clinical Cardiology·Gianluca IacobellisUmberto Di Mario
Nov 25, 2004·JAMA : the Journal of the American Medical Association·Thomas J WangEmelia J Benjamin
Jan 5, 2006·Nature Clinical Practice. Cardiovascular Medicine·Yuji Matsuzawa
Mar 11, 2006·European Heart Journal·Jan HeeringaJacqueline C M Witteman
Jun 2, 2007·American Heart Journal·Harold S Sacks, John N Fain
Dec 18, 2007·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Alexis E MalavazosBruno Ambrosi
Dec 19, 2007·Circulation·Wayne RosamondUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Dec 25, 2007·Gender Medicine·Vera Regitz-ZagrosekShokufeh Mahmoodzadeh
Jan 6, 2009·Diabetes Care·UNKNOWN American Diabetes Association
May 27, 2010·JAMA : the Journal of the American Medical Association·Brent M EganR Neal Axon
May 28, 2010·Circulation. Arrhythmia and Electrophysiology·Omar BatalMina K Chung
Aug 28, 2010·Journal of the American College of Cardiology·M Obadah Al ChekakieJoseph G Akar
Sep 17, 2010·The Journal of Clinical Endocrinology and Metabolism·Jiankang LiuHerman A Taylor
Apr 23, 2011·Journal of the American College of Cardiology·Christopher X WongPrashanthan Sanders
May 6, 2011·Diabetes Care·Patricia Iozzo
Mar 25, 2014·The American Journal of Cardiology·Tomasz MazurekGrzegorz Opolski
Oct 13, 2014·The American Journal of Cardiology·Ricardo Fontes-CarvalhoAdelino Leite-Moreira

❮ Previous
Next ❯

Citations

Feb 14, 2017·The Journal of Physiology·Alexios S Antonopoulos, Charalambos Antoniades
Mar 8, 2017·Expert Review of Cardiovascular Therapy·Louisa O'NeillSteven E Williams
Nov 7, 2018·Journal of Thoracic Imaging·Gastón A Rodríguez-GranilloPatricia Carrascosa

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Related Papers

Journal of Cardiovascular Electrophysiology
Krit JongnarangsinFred Morady
Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır
Ilker MataraciKaan Kirali
© 2021 Meta ULC. All rights reserved