Abstract
Using immunohistochemistry the expression of galanin (GAL) and galanin message-associated peptide (GMAP) in the superior cervical ganglion (SCG) was investigated 2, 4, 7, and 14 days after unilateral transection of the cervical sympathetic trunk (decentralization) or after cutting the external and internal carotid nerves (axotomy), as well as 7 days after removal of parotid gland tissue. In control SCGs including the sympathetic trunk and the carotid nerves, very few neurons and fibers were GAL/GMAP-positive. Two and 7 days after decentralization, about 5% of all counted neuron profiles in the ipsilateral SCG were GAL/GMAP immunoreactive. Immunoreactive cell bodies were distributed throughout the SCG, with a greater number in the most caudal portion of the ganglion. Many GAL/GMAP-positive nerve fibers were observed in the whole SCG, with strongly fluorescent bundles of immunoreactive fibers accumulated at the caudal end of the SCG. Several GAL/GMAP-immunoreactive nerve fibers were seen ipsilaterally in the external carotid nerve, whereas only a few positive fibers could be observed in the internal carotid nerve. About 2% of all counted neuron profiles in SCGs ipsilateral to decentralization still contained GAL/GMAP-immunoreacti...Continue Reading
Citations
Dec 19, 2013·ISRN Neurology·Pablo R Brumovsky
Jul 16, 2003·The European Journal of Neuroscience·Bartłomiej Szulczyk, Paweł Szulczyk
May 17, 2005·Neuroscience·K HolmbergT Hökfelt
Sep 1, 1996·Microscopy Research and Technique·L KlimaschewskiC Heym
Apr 16, 2004·Journal of Neurobiology·Kristen L BoeshoreRichard E Zigmond
Oct 3, 2002·Journal of Neurobiology·Rebecca C SchreiberRichard E Zigmond
Feb 1, 1996·Molecular Neurobiology·S R Whittemore, E Y Snyder
Oct 1, 1996·The European Journal of Neuroscience·Y Sun, R E Zigmond
Nov 28, 2014·Pharmacological Reviews·Roland LangBarbara Kofler
Aug 1, 1996·Journal of Neurobiology·H Hyatt-SachsR E Zigmond
Mar 13, 2009·Developmental Neurobiology·Beth A HabeckerRichard E Zigmond
Sep 1, 1996·Microscopy Research and Technique·R Roivainen, J Koistinaho
Feb 13, 2001·Experimental Neurology·K HolmbergT Hökfelt
Jan 1, 1996·Life Sciences·J N Crawley
May 1, 1997·Neuroscience·S KroesenL Klimaschewski
Jul 1, 1997·Brain Research. Molecular Brain Research·J D CornessT Hökfelt
Sep 22, 1995·Regulatory Peptides·J N Crawley