Increased fes1a thermotolerance is induced by BAG6 knockout

Plant Molecular Biology
Can FuJian Liu

Abstract

KEY MESSAGE: (1) The fes1a bag6 double mutant shows an increased short term thermotolerance compared to fes1a. BAG6 is a suppressor of Fes1A; (2) IQ motif is essential to effective performance of BAG6. (3) Calmodulin was involved in signal transduction. (4) BAG6 is localized in the nucleus. HSP70s play an important role in the heat-induced stress tolerance of plants. However, effective HSP70 function requires the assistance of many co-chaperones. BAG6 and Fes1A are HSP70-binding proteins that are critical for Arabidopsis thaliana thermotolerance. Despite this importance, little is known about how these co-chaperones interact. In this study, we assessed the thermotolerance of a fes1a bag6 double mutant. We found that the fes1a bag6 double mutant shows an increased short-term thermotolerance compared to fes1a. However, calmodulin inhibitors diminished this enhanced thermotolerance in the fes1a bag6 double mutant. In addition, we found the IQ motif to be essential for effective BAG6 performance. Since BAG6 is localized in the nucleus, the signal transduction is likely to involve nuclear calcium signaling.

References

Sep 5, 2002·The Plant Journal : for Cell and Molecular Biology·Veena SangwanRajinder S Dhindsa
Sep 25, 2003·Journal of Cellular Biochemistry·Tomasz T CalikowskiIris Meier
Apr 26, 2006·The Journal of Biological Chemistry·Elena V DoukhaninaMartin B Dickman
Feb 12, 2008·Cellular and Molecular Life Sciences : CMLS·M Kabbage, M B Dickman
May 10, 2008·The Plant Journal : for Cell and Molecular Biology·Hong-Tao LiuRen-Gang Zhou
Mar 17, 2010·Proceedings of the National Academy of Sciences of the United States of America·Brett WilliamsMartin B Dickman
Jun 12, 2010·The Plant Journal : for Cell and Molecular Biology·Jing-Xia ZhangJian Liu
Mar 30, 2011·Plant, Cell & Environment·Annelies InzéFrank Van Breusegem
Sep 1, 2006·Plant Science : an International Journal of Experimental Plant Biology·Shu-Ying YiJian Liu
Nov 6, 2012·Molecular Cell·Roman KitykMatthias P Mayer
Jun 12, 2013·Plant Physiology·Myriam Charpentier, Giles E D Oldroyd
Sep 10, 2013·Trends in Biochemical Sciences·Matthias P Mayer
Nov 19, 2015·Plant, Cell & Environment·Sira Echevarría-ZomeñoM Mar Castellano
Apr 30, 2016·Plant Signaling & Behavior·Yurong Li, Marty Dickman
Aug 20, 2016·Scientific Reports·Luhua LiYuequan Shen
Apr 27, 2017·Biochemical and Biophysical Research Communications·Shijuan FuYuequan Shen

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Citations

Jan 30, 2021·Frontiers in Plant Science·Richa BabbarChristine H Foyer
Jun 3, 2021·International Journal of Molecular Sciences·Muhammad ArifShuzhen Men

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Methods Mentioned

BETA
nucleotide exchange
transgenic
co-immunoprecipitation
PCR

Software Mentioned

PSORT

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