Increased hippocampal volumes in adults with high functioning autism spectrum disorder and an IQ>100: A manual morphometric study

Psychiatry Research
Simon MaierAndreas Riedel

Abstract

Previous studies concerning the volumes of the amygdala and the hippocampus in autism spectrum disorders (ASD) show inconsistent results. We acquired magnetic resonance images of 30 individuals with ASD and individually matched controls. All participants had an IQ>100 to increase the likelihood of including non-syndromal forms of ASD. Manually defined amygdala volumes showed no significant group difference, while hippocampi were significantly enlarged in ASD. This finding is discussed with regard to the 'intense world hypothesis'.

References

Sep 26, 2001·Brain : a Journal of Neurology·K PierceE Courchesne
Aug 15, 2002·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Heather CodyJoseph Piven
May 28, 2004·Journal of Autism and Developmental Disorders·Simon Baron-Cohen, Sally Wheelwright
Jul 16, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Cynthia Mills SchumannDavid G Amaral
Dec 6, 2006·Archives of General Psychiatry·Brendon M NacewiczRichard J Davidson
May 6, 2009·Archives of General Psychiatry·Matthew W MosconiJoseph Piven
Sep 4, 2009·Biological Psychiatry·Cynthia Mills SchumannEric Courchesne
Oct 13, 2009·Lancet·Susan E LevyRobert T Schultz
Dec 31, 2010·Frontiers in Human Neuroscience·Kamila Markram, Henry Markram
Jun 23, 2011·Journal of Neurology, Neurosurgery, and Psychiatry·Franco CaudaRoberto Keller
Sep 29, 2011·Autism Research : Official Journal of the International Society for Autism Research·Clodagh M MurphyD G Murphy
Dec 6, 2011·Autism Research : Official Journal of the International Society for Autism Research·Emma G DuerdenS Wendy Roberts

❮ Previous
Next ❯

Citations

Jun 18, 2016·Frontiers in Neuroscience·Tehila Eilam-StockJin Fan
Jul 26, 2016·Frontiers in Neuroscience·Bernard J Crespi
Aug 25, 2019·Journal of Autism and Developmental Disorders·Kenta Yamamoto, Kouhei Masumoto
Apr 7, 2018·Journal of Autism and Developmental Disorders·Kenta Yamamoto, Kouhei Masumoto
Oct 3, 2018·Cerebral Cortex·Kirsten M LynchUNKNOWN Pediatric Imaging, Neurocognition and Genetics Study

❮ Previous
Next ❯

Related Concepts

Related Feeds

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Autism

Autism spectrum disorder is associated with challenges with social skills, repetitive behaviors, and often accompanied by sensory sensitivities and medical issues. Here is the latest research on autism.

Related Papers

Autism : the International Journal of Research and Practice
Dermot Bowler
Autism : the International Journal of Research and Practice
Sven Bölte
The Journal of the South Carolina Medical Association
Laura A Carpenter, Michelle M Macias
© 2021 Meta ULC. All rights reserved