Increased incidence of coronary artery disease in sleep apnoea: a long-term follow-up

The European Respiratory Journal
Y PekerJ Hedner

Abstract

An increased incidence of cardiovascular disease has previously been reported in middle-aged males during a follow-up period of 7 yrs. The aim of the present study was to address the incidence of coronary artery disease (CAD) in a larger sample without any heart disease at baseline. The population comprised 308 snorers (245 males and 63 females) with a mean +/- sd age of 49.0 +/- 9.9 yrs in 1991. Data were collected via the Swedish Hospital Discharge Register, National Cause of Death Registry, clinical charts and questionnaires. Over 7 yrs, CAD was observed in 17 (16.2%) of 105 patients with obstructive sleep apnoea (OSA; overnight (6 h) oxygen desaturations > or =30 events) compared with 11 (5.4%) of 203 snorers without OSA. OSA diagnosis at baseline was associated with an increased risk of development of CAD in a multivariate model. In the OSA group, CAD was confirmed in 16 (24.6%) of 65 incompletely treated patients compared with one (3.9%) of 26 efficiently treated subjects. Efficient treatment of OSA reduced this risk. It is concluded that middle-aged sleep apnoeics are at high risk of developing coronary artery disease if they are not treated efficiently, which should be considered in cardiovascular disease prevention mod...Continue Reading

Citations

Aug 10, 2010·Wiener medizinische Wochenschrift·Christian PrinzOlaf Oldenburg
Sep 2, 2008·Heart Failure Reviews·Martin A Valdivia-ArenasRami N Khayat
Sep 25, 2009·Sleep & Breathing = Schlaf & Atmung·Neomi A ShahVahid Mohsenin
Feb 2, 2012·Sleep & Breathing = Schlaf & Atmung·Christine H WonPaul A Heidenreich
Mar 21, 2012·Sleep & Breathing = Schlaf & Atmung·Junichiro HayanoKeisaku Fujimoto
Apr 25, 2012·Sleep & Breathing = Schlaf & Atmung·Katherine M SharkeyRichard P Millman
Oct 24, 2012·Sleep & Breathing = Schlaf & Atmung·Neomi ShahRobert C Kaplan
Sep 16, 2010·Current Treatment Options in Cardiovascular Medicine·David E Green, David A Schulman
Nov 16, 2007·Comprehensive Therapy·Wilbert S Aronow
Sep 26, 2012·Nature Reviews. Cardiology·Jean-Philippe BaguetJean-Louis Pépin
Sep 17, 2010·Seminars in Reproductive Medicine·Hadine JoffeKatherine M Sharkey
May 22, 2007·Antioxidants & Redox Signaling·Vivek Jain
Nov 16, 2010·The Journal of Cardiovascular Nursing·Judith L Reishtein
Dec 15, 2010·The Neurologist·Kanika Bagai
Jun 11, 2009·Diabetes, Obesity & Metabolism·Iskandar IdrisJohn P Wilding
Nov 18, 2010·Circulation. Cardiovascular Quality and Outcomes·Judith H LichtmanHarlan M Krumholz
Feb 3, 2007·American Journal of Respiratory and Critical Care Medicine·Ali A El SolhCorey R Mankowski
Mar 2, 2011·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Lyudmila S KorostovtsevaAlexander L Kalinkin
Feb 6, 2008·Proceedings of the American Thoracic Society·Naresh M Punjabi
Feb 16, 2012·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Sophia E SchizaNikolaos M Siafakas
Jul 16, 2013·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·John A GjevreDavid Cotton
Sep 3, 2013·American Journal of Respiratory and Critical Care Medicine·Richard J SchwabUNKNOWN ATS Subcommittee on CPAP Adherence Tracking Systems
May 2, 2014·The American Journal of Case Reports·Lyudmila KorostovtsevaAlexandra Konradi
Mar 29, 2014·American Journal of Respiratory and Critical Care Medicine·Francisco Campos-RodriguezCarmen V Almeida-Gonzalez
Mar 22, 2014·Revue de pneumologie clinique·H Ben AhmedM R Boujnah
Jul 2, 2014·Annals of the American Thoracic Society·Shiraz A NisarOmar A Minai
Mar 7, 2014·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Gholam K Motamedi
Jan 7, 2011·Sleep & Breathing = Schlaf & Atmung·Denis MartinezMiguel Gus
Feb 25, 2014·Sleep & Breathing = Schlaf & Atmung·Guoda PilkauskaiteRaimundas Sakalauskas
Mar 4, 2014·Sleep & Breathing = Schlaf & Atmung·S MorongN de Vries
Aug 20, 2014·Current Cardiology Reports·B Cepeda-ValeryA S Gami
Nov 25, 2014·Seminars in Nephrology·Angela Yee-Moon Wang
Sep 8, 2010·Journal of Women's Health·Katherine M SharkeyRichard P Millman
Jun 3, 2008·Therapeutics and Clinical Risk Management·Punginathn Dorasamy
Mar 30, 2013·Current Cardiovascular Risk Reports·Carlos Iribarren, Sabee Molloi
Jul 23, 2013·Current Cardiology Reports·Athanasia Pataka, Renata L Riha
Nov 28, 2008·Der Internist·V TöpferH Magnussen
Jun 24, 2008·Platelets·Darija BakovicZeljko Dujic
Jul 30, 2008·Scandinavian Cardiovascular Journal : SCJ·Yüksel PekerJan Ejdebäck
Nov 16, 2007·The American Journal of the Medical Sciences·Susmita ChowdhuriM Safwan Badr
Jul 25, 2007·Chest·Naresh M PunjabiNeal Fedarko
Apr 9, 2016·Indian Heart Journal·Stefan D AnkerRobin Germany

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