PMID: 5910013Apr 1, 1966

Increased incidence of lymphoma after injections of mice with cells differing at weak histocompatibility loci

Science
R L Walford

Abstract

Newborns of two congenic strains of mice, in which the incidence of leukemia is low, differing only at the weak H-1 locus, were. injected at birth with adult spleen cells of the parent and of the congenic strain. A marked increase in the incidence of lymphoma ensued in those mice of both strains injected with cells from the other strain. The experiment lends some support to the idea that transplantation immunologic mechanisms may play a role in the genesis of lymphomas.

Citations

Oct 1, 1973·Social Science & Medicine·D A Kennedy
Nov 1, 1983·Human Immunology·V E Von FliednerM Wyss
Mar 29, 1969·Lancet·D W Smithers, E O Field
Jan 1, 1969·Transplantation Reviews·T E StarziC W Putnam
Jan 1, 1971·Transplantation Reviews·R L WalfordH Waters
Jan 1, 1976·Transplantation Reviews·S K Datta, R S Schwartz
Jan 9, 1982·British Medical Journal·J R Curtis
Aug 1, 1974·Journal of Neurology, Neurosurgery, and Psychiatry·L B Barnett, E Schwartz
May 1, 1967·The Journal of Clinical Investigation·J N SheagrenS M Wolff
May 15, 1971·Lancet·S A Schneck, I Penn
Jan 15, 1973·International Journal of Cancer. Journal International Du Cancer·T Nemirovsky, N Trainin
Nov 1, 1977·Journal of Chronic Diseases·A R NissensonP L Nausieda
Mar 1, 1977·Clinical Immunology and Immunopathology·J A LevyR S Schwartz
Jun 1, 1980·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R C Hard, S S Cross
Nov 20, 1981·The Journal of Comparative Neurology·W S GriffinJ R Head
Feb 1, 1994·Contact Dermatitis·V Ziegler, B Ziegler
Jan 1, 1969·Pathology·D Keast, N F Stanley
Nov 21, 1973·Nature: New Biology·N Haran-Ghera
Feb 1, 1985·Drug Intelligence & Clinical Pharmacy·R J PtachcinskiR Venkataramanan
Dec 1, 1974·The British Journal of Dermatology·R S TanP D Samman
Jan 1, 1985·Critical Reviews in Clinical Laboratory Sciences·H Bril, R Benner

Related Concepts

Lymphoma
Neoplasm Transplantation
Neoplasms, Experimental
Spleen
Transplantation Immunology
Transplantation, Homologous

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.