PMID: 37502Jun 1, 1979

Increased levels of adenosine 3',5'-cyclic monophosphate in Tetrahymena stimulated by glucose and mediated by Ca2+ and epinephrine

Proceedings of the National Academy of Sciences of the United States of America
S G Nandini-Kishore, G A Thompson

Abstract

Stationary phase Tetrahymena cells exposed to 0.5-1% glucose experience an 8-fold increase in intracellular cyclic AMP within 1 hr. The increase follows an enhanced uptake of Ca2+ triggered by the glucose addition. Inhibiting the Ca2+ influx with ethylene glycol bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid blocks the increase in cyclic AMP, but the block can be reversed by the addition of epinephrine. Both this epinephrine effect and the glucose-induced increase in cyclic AMP are counteracted by the beta-adrenergic inhibitor dichloroisoproterenol.

References

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Jul 1, 1992·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·G T TsangarisV M Kapoulas
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Jan 1, 1976·Comparative Biochemistry and Physiology. A, Comparative Physiology·M Aomine
Jun 1, 1976·FEBS Letters·J R DickinsonB E Swoboda
Apr 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·C T Roberts, D E Morse
May 1, 1976·The Journal of Cell Biology·G FisherP D Peters
Jun 4, 1976·Biochimica Et Biophysica Acta·H G Hansma, C Kung
Sep 1, 1969·Proceedings of the National Academy of Sciences of the United States of America·A L SteinerC Parker
Jul 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·J J Blum
May 5, 1972·Science·R Eckert
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Apr 1, 1970·The Journal of General Physiology·R Eckert, Y Naitoh

Related Concepts

Ethylene Glycol Measurement
Adenosine
Calcium
Protoplasm
Uptake
Ethers
Cyclic AMP
Etherum, ether, Homeopathic preparation
Tetrahymena
Cyclic Adenosine Monophosphate Measurement

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