PMID: 9186284Jan 1, 1997Paper

Increased lipoprotein (a) and its relationships with other parameters of lipoprotein metabolism in chronic renal failure treated by hemodialysis

Japanese Heart Journal
M R YiğitoğluH M Ozilgili

Abstract

Studies have shown that patients with chronic renal failure have a high frequency of cardiovascular atheromatous disease. We examined serum lipoprotein (a) [Lp(a)], very-low density lipoprotein cholesterol (VLDL-C), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C), apolipoprotein A1 (apo A1) and B (apo B), triglyceride (TG) and total cholesterol (TC) levels as possible risk factors for atherosclerosis in 45 patients with chronic renal failure (CRF) treated by hemodialysis (HD) and in 15 CRF patients who were not on HD. A control group of 20 healthy subjects was also studied. The proportion of smokers and body mass indexes were similar between the groups. In both patient groups, higher TG, TC and Lp(a) and lower apo A1 and HDL-C levels in serum were found than in those of controls. Serum apo B and LDL-C were similar in the patients treated by HD and the controls. Serum VLDL-C and LDL-C were similar in the CRF patients who were not on HD and the controls. The highest ratios of apo B/apo A1 and LDL-C/HDL-C were found in HD patients. The highest ratio of TC/HDL-C was found in the other patient group. We found significant correlations between Lp(a) and other parameters of lipoprotein metab...Continue Reading

Citations

Feb 7, 2007·International Urology and Nephrology·H Abo-ZenahM Sobh
Oct 3, 2012·International Journal of Nephrology·Hiroyuki ImamuraReika Oshikata
Aug 29, 2000·Journal of Clinical Pathology·H J MilionisD P Mikhailidis
Apr 15, 1999·Journal of the American Society of Nephrology : JASN·G MetryB G Danielson

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