Increased microbicidal activity of green tea (Camellia sinensis) in combination with butylated hydroxyanisole

Journal of Chemotherapy
G SimonettiA Villa

Abstract

We have demonstrated that green tea (Camellia sinensis) shows increased antimicrobial activity against bacteria and fungi when used in combination with butylated hydroxyanisole (BHA). Glycolic extract taken from green tea showed only limited activity against Streptococcus mutans and no activity against Candida albicans and certain strains of Escherichia coli. BHA, at non inhibitory concentrations, increased the microbicidal activity of green tea against 10(10) S. mutans (p<0.01), non-susceptible E. coli (p<0.01) and C. albicans (p<0.01). Green tea in combination with BHA reduced the hydrophobicity of S. mutans (p<0.01) and greatly inhibited (p<0.001) the formation of hyphae in C. albicans. The increased antimicrobial activity of green tea is related to an impairment of the barrier function in microorganisms and a depletion of thiol groups. The increased activity of green tea as an oral antimicrobial product is discussed.

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Citations

Aug 3, 2014·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·José Manuel Pérez MartínMaría José Hazen
Jul 5, 2008·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Shanmugam HemaiswaryaMukesh Doble
Feb 13, 2015·Critical Reviews in Food Science and Nutrition·Md Wasim SiddiquiR S Dhua
Dec 1, 2005·Phytotherapy Research : PTR·Jeffrey D LautenTheresa E Madden
Jun 12, 2020·Nigerian Journal of Clinical Practice·B GokM Kivanc
Dec 10, 2009·International Journal of Dental Hygiene·H I AwadallaM O Abbas

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