Increased mortality in women with cataract: a population based follow up of the North London Eye Study

The British Journal of Ophthalmology
A ReidyA Connolly

Abstract

In diabetics, cataract is associated with higher risk of death. In non-diabetics the data are conflicting, but some indicate an association between one type of cataract (nuclear) and increased mortality. The aim of this study was to estimate and compare age and sex specific mortality for elderly people with and without cataract in a population based cohort. A random sample drawn from a defined population of elderly people (age 65 and older) registered with 17 general practice groups in north London formed the study cohort and were followed up for 4 years. The age and sex specific mortality from various causes was estimated and compared in those with and without cataract. In non-diabetics (n=1318), cataract (lens opacity at baseline) was significantly associated with higher mortality in women. The age standardised death rate per 1000 was 39.8 and 24.8 in women with and without cataract, respectively (age adjusted hazard ratio 1.7, confidence limits 1.1 to 2.7, p=0.032). This was not the case in non-diabetic men (hazard ratio 0.9, confidence limits 0.6 to 1.5, p=0.782). The excess mortality in women with cataract was consistent for cardiovascular, respiratory, and other non-cancer causes of death. There was no association between...Continue Reading

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Citations

Nov 5, 2002·Nature Reviews. Cancer·Michael J Tisdale
May 25, 2007·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·George S ZubenkoNorman S Wolf
Aug 4, 2006·The British Journal of Ophthalmology·M C GrieshaberS Orgül
Sep 4, 2007·Ophthalmology·Athena W P FoongPaul J Foster
Aug 19, 2010·BMC Geriatrics·William R SwindellUNKNOWN Study Of Osteoporotic Fractures Research Group
Jun 9, 2016·The British Journal of Ophthalmology·Benjamin J ThomasGeoffrey C Tabin
Jan 27, 2006·Current Opinion in Ophthalmology·Steven Dewey
Feb 28, 2006·European Journal of Ageing·Laurence Seematter-Bagnoud, Brigitte Santos-Eggimann
Apr 5, 2011·European Journal of Ophthalmology·M Amparo Díez-AjenjoJosé Luis Menezo

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